You are here: Research > Publications
  • Deutsch
  • ǀEnglish

Publications

MicroRNA-155 and macrophages: a fatty liaison.
Hartmann P, Schober A, Weber C
.
Cardiovasc Res. 2014 Jul 1;103(1):5-6. doi: 10.1093/cvr/cvu135. Epub 2014 Jun 6. No abstract available.

Polymorphic Variants of Adrenoceptors: Pharmacology, Physiology, and Role in Disease.

Ahles A, Engelhardt S.
Pharmacol Rev. 2014 Jul;66(3):598-637. Review.

Genetic determinants of circulating interleukin-1 receptor antagonist levels and their association with glycemic traits.
Herder C, Nuotio ML, Shah S, Blankenberg S, Brunner EJ, Carstensen M, Gieger C, Grallert H, Jula A, Kähönen M, Kettunen J, Kivimäki M, Koenig W, Kristiansson K, Langenberg C, Lehtimäki T, Luotola K, Marzi C, Müller C, Peters A, Prokisch H, Raitakari O, Rathmann W, Roden M, Salmi M, Schramm K, Swerdlow D, Tabak AG, Thorand B, Wareham N, Wild PS, Zeller T, Hingorani AD, Witte DR, Kumari M, Perola M, Salomaa V.
Diabetes. 2014 Jun 26. pii: DB_140731. [Epub ahead of print]

Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization.
Arking DE, Pulit SL, Crotti L, van der Harst P, Munroe PB, Koopmann TT, Sotoodehnia N, Rossin EJ, Morley M, Wang X, Johnson AD, Lundby A, Gudbjartsson DF, Noseworthy PA, Eijgelsheim M, Bradford Y, Tarasov KV, Dörr M, Müller-Nurasyid M, Lahtinen AM, Nolte IM, Smith AV, Bis JC, Isaacs A, Newhouse SJ, Evans DS, Post WS, Waggott D, Lyytikäinen LP, Hicks AA, Eisele L, Ellinghaus D, Hayward C, Navarro P, Ulivi S, Tanaka T, Tester DJ, Chatel S, Gustafsson S, Kumari M, Morris RW, Naluai AT, Padmanabhan S, Kluttig A, Strohmer B, Panayiotou AG, Torres M, Knoflach M, Hubacek JA, Slowikowski K, Raychaudhuri S, Kumar RD, Harris TB, Launer LJ, Shuldiner AR, Alonso A, Bader JS, Ehret G, Huang H, Kao WH, Strait JB, Macfarlane PW, Brown M, Caulfield MJ, Samani NJ, Kronenberg F, Willeit J; CARe Consortium; COGENT Consortium, Smith JG, Greiser KH, Meyer Zu Schwabedissen H, Werdan K, Carella M, Zelante L, Heckbert SR, Psaty BM, Rotter JI, Kolcic I, Polašek O, Wright AF, Griffin M, Daly MJ; DCCT/EDIC, Arnar DO, Hólm H, Thorsteinsdottir U; eMERGE Consortium, Denny JC, Roden DM, Zuvich RL, Emilsson V, Plump AS, Larson MG, O'Donnell CJ, Yin X, Bobbo M, D'Adamo AP, Iorio A, Sinagra G, Carracedo A, Cummings SR, Nalls MA, Jula A, Kontula KK, Marjamaa A, Oikarinen L, Perola M, Porthan K, Erbel R, Hoffmann P, Jöckel KH, Kälsch H, Nöthen MM; HRGEN Consortium, den Hoed M, Loos RJ, Thelle DS, Gieger C, Meitinger T, Perz S, Peters A, et al., Kääb S, Chakravarti A, Ackerman MJ, Pfeufer A, de Bakker PI, Newton-Cheh C.
Nat Genet. 2014 Jun 22. doi: 10.1038/ng.3014. [Epub ahead of print]

Label-free determination of hemodynamic parameters in the microcirculaton with third harmonic generation microscopy.
Dietzel S, Pircher J, Nekolla AK, Gull M, Brändli AW, Pohl U, Rehberg M.
PLoS One. 2014 Jun 16;9(6):e99615. doi: 10.1371/journal.pone.0099615. eCollection 2014.

The CXCL12/CXCR4 chemokine ligand/receptor axis in cardiovascular disease.
Döring Y, Pawig L, Weber C, Noels H.
Front Physiol. 2014 Jun 11;5:212. doi: 10.3389/fphys.2014.00212. eCollection 2014. Review.

Novel Calmodulin (CALM2) Mutations Associated with Congenital Arrhythmia Susceptibility.
Makita N, Yagihara N, Crotti L, Johnson CN, Beckmann BM, Roh MS, Shigemizu D, Lichtner P, Ishikawa T, Aiba T, Homfray T, Behr ER, Klug D, Denjoy I, Mastantuono E, Theisen D, Tsunoda T, Satake W, Toda T, Nakagawa H, Tsuji Y, Tsuchiya T, Yamamoto H, Miyamoto Y, Endo N, Kimura A, Ozaki K, Motomura H, Suda K, Tanaka T, Schwartz PJ, Meitinger T, Kääb S, Guicheney P, Shimizu W, Bhuiyan ZA, Watanabe H, Chazin WJ, George AL.
Circ Cardiovasc Genet. 2014 Jun 10. pii: CIRCGENETICS.113.000459. [Epub ahead of print]

Mendelian randomization studies in coronary artery disease.
Jansen H, Samani NJ, Schunkert H.
Eur Heart J. 2014 Jun 10. pii: ehu208. [Epub ahead of print] Review.

MRTF-A controls vessel growth and maturation by increasing the expression of CCN1 and CCN2.
Hinkel R, Trenkwalder T, Petersen B, Husada W, Gesenhues F, Lee S, Hannappel E, Bock-Marquette I, Theisen D, Leitner L, Boekstegers P, Cierniewski C, Müller OJ, le Noble F, Adams RH, Weinl C, Nordheim A, Reichart B, Weber C, Olson E, Posern G, Deindl E, Niemann H, Kupatt C.
Nat Commun. 2014 Jun 9;5:3970. doi: 10.1038/ncomms4970.

Atherosclerosis-Multiple Pathways to Lesional Macrophages.
Schulz C, Massberg S.
Sci Transl Med. 2014 Jun 4;6(239):239ps2. Review.

Postextrasystolic blood pressure potentiation predicts poor outcome of cardiac patients.
Sinnecker D, Dirschinger RJ, Barthel P, Müller A, Morley-Davies A, Hapfelmeier A, Dommasch M, Huster KM, Hasenfuss G, Laugwitz KL, Malik M, Schmidt G.
J Am Heart Assoc. 2014 Jun 3;3(3). pii: e000857. doi: 10.1161/JAHA.114.000857.

Potential confounders of signal-averaged P-wave duration--strenuous exercise and catecholamines.
Scherr J, Halle M.
Scand J Med Sci Sports. 2014 Jun;24(3):602. doi: 10.1111/sms.12099. No abstract available.

Remote monitoring of implantable cardioverter-defibrillators : Problems and implications using a telemonitoring system.
Siebermair J, Clauss S, Martens E, Schuessler F, Oversohl N, Haserueck N, Estner HL, Kääb S, Wakili R.
Herz. 2014 May 23. [Epub ahead of print]

Weight of the bleeding impact on early and late mortality after percutaneous coronary intervention.
Ndrepepa G, Guerra E, Schulz S, Fusaro M, Cassese S, Kastrati A.
J Thromb Thrombolysis. 2014 May 16. [Epub ahead of print]

NO, via its target Cx37, modulates calcium signal propagation selectively at myoendothelial gap junctions.
Pogoda K, Füller M, Pohl U, Kameritsch P.
Cell Commun Signal. 2014 May 15;12(1):33. doi: 10.1186/1478-811X-12-33.

Prasugrel plus bivalirudin vs. clopidogrel plus heparin in patients with ST-segment elevation myocardial infarction.
Schulz S, Richardt G, Laugwitz KL, Morath T, Neudecker J, Hoppmann P, Mehran R, Gershlick AH, Tölg R, Anette Fiedler K, Abdel-Wahab M, Kufner S, Schneider S, Schunkert H, Ibrahim T, Mehilli J, Kastrati A; and for the Bavarian Reperfusion Alternatives Evaluation (BRAVE) 4 Investigators.
Eur Heart J. 2014 May 9. [Epub ahead of print]

There's life in the old dog yet: Clopidogrel competing with prasugrel and ticagrelor for treatment of ACS patients.
Sibbing D, Massberg S.
Thromb Haemost. 2014 May 8;112(1). [Epub ahead of print] No abstract available.

Risk stratification for sudden cardiac death: current status and challenges for the future.
Wellens HJ, Schwartz PJ, Lindemans FW, Buxton AE, Goldberger JJ, Hohnloser SH, Huikuri HV, Kääb S, La Rovere MT, Malik M, Myerburg RJ, Simoons ML, Swedberg K, Tijssen J, Voors AA, Wilde AA.
Eur Heart J. 2014 May 5. [Epub ahead of print]

Correlates of poor outcome among patients with bleeding after coronary interventions.
Ndrepepa G, Guerra E, Schulz S, Hoppmann P, Laugwitz KL, Kastrati A.
Coron Artery Dis. 2014 May 5. [Epub ahead of print]

Assessment of mean respiratory rate from ECG recordings for risk stratification after myocardial infarction.
Sinnecker D, Dommasch M, Barthel P, Müller A, Dirschinger RJ, Hapfelmeier A, Huster KM, Laugwitz KL, Malik M, Schmidt G.
J Electrocardiol. 2014 May 4. pii: S0022-0736(14)00153-8. doi: 10.1016/j.jelectrocard.2014.04.021. [Epub ahead of print]

Microvascular obstruction in patients with non-ST-elevation myocardial infarction: a contrast-enhanced cardiac magnetic resonance study.
Guerra E, Hadamitzky M, Ndrepepa G, Bauer C, Ibrahim T, Ott I, Laugwitz KL, Schunkert H, Kastrati A.
Int J Cardiovasc Imaging. 2014 Apr 30. [Epub ahead of print]

Programming and isolation of highly pure physiologically and pharmacologically functional sinus-nodal bodies from pluripotent stem cells.
Jung JJ, Husse B, Rimmbach C, Krebs S, Stieber J, Steinhoff G, Dendorfer A, Franz WM, David R.
Stem Cell Reports. 2014 Apr 17;2(5):592-605. doi: 10.1016/j.stemcr.2014.03.006. eCollection 2014 May 6.

Synchronized integrin engagement and chemokine activation is crucial in neutrophil extracellular trap-mediated sterile inflammation.
Rossaint J, Herter JM, Van Aken H, Napirei M, Döring Y, Weber C, Soehnlein O, Zarbock A.
Blood. 2014 Apr 17;123(16):2573-84. doi: 10.1182/blood-2013-07-516484. Epub 2013 Dec 12.

Cardiac fibroblast-derived microRNA passenger strand-enriched exosomes mediate cardiomyocyte hypertrophy.
Bang C, Batkai S, Dangwal S, Gupta SK, Foinquinos A, Holzmann A, Just A, Remke J, Zimmer K, Zeug A, Ponimaskin E, Schmiedl A, Yin X, Mayr M, Halder R, Fischer A, Engelhardt S, Wei Y, Schober A, Fiedler J, Thum T.
J Clin Invest. 2014 Apr 17. pii: 70577. doi: 10.1172/JCI70577. [Epub ahead of print]

Mapping the genetic architecture of gene regulation in whole blood.
Schramm K, Marzi C, Schurmann C, Carstensen M, Reinmaa E, Biffar R, Eckstein G, Gieger C, Grabe HJ, Homuth G, Kastenmüller G, Mägi R, Metspalu A, Mihailov E, Peters A, Petersmann A, Roden M, Strauch K, Suhre K, Teumer A, Völker U, Völzke H, Wang-Sattler R, Waldenberger M, Meitinger T, Illig T, Herder C, Grallert H, Prokisch H.
PLoS One. 2014 Apr 16;9(4):e93844. doi: 10.1371/journal.pone.0093844. eCollection 2014.

Cathelicidin LL-37 induces time-resolved release of LTB4 and TXA2 by human macrophages and triggers eicosanoid generation in vivo.
Wan M, Soehnlein O, Tang X, van der Does AM, Smedler E, Uhlén P, Lindbom L, Agerberth B, Haeggström JZ.
FASEB J. 2014 Apr 15. [Epub ahead of print]

A comparative cohort study on personalised antiplatelet therapy in PCI-treated patients with high on-clopidogrel platelet reactivity. Results of the ISAR-HPR registry.
Mayer K, Schulz S, Bernlochner I, Morath T, Braun S, Hausleiter J, Massberg S, Schunkert H, Laugwitz KL, Kastrati A, Sibbing D.
Thromb Haemost. 2014 Apr 10;112(2). [Epub ahead of print]

Deficiency of Endothelial Cxcr4 Reduces Reendothelialization and Enhances Neointimal Hyperplasia After Vascular Injury in Atherosclerosis-Prone Mice.
Noels H, Zhou B, Tilstam PV, Theelen W, Li X, Pawig L, Schmitz C, Akhtar S, Simsekyilmaz S, Shagdarsuren E, Schober A, Adams RH, Bernhagen J, Liehn EA, Döring Y, Weber C.
Arterioscler Thromb Vasc Biol. 2014 Apr 10. [Epub ahead of print]

Prognostic value of bleeding after percutaneous coronary intervention in patients with diabetes.
Ndrepepa G, Schulz S, Neumann FJ, Laugwitz KL, Richardt G, Byrne RA, Pöhler A, Kastrati A, Pache J.
EuroIntervention. 2014 Apr 3. pii: 20130502-03. [Epub ahead of print]

Safety and efficacy of a potential treatment algorithm by using manual compression repair and ultrasound-guided thrombin injection for the management of iatrogenic femoral artery pseudoaneurysm in a large patient cohort.
Dzijan-Horn M, Langwieser N, Groha P, Bradaric C, Linhardt M, Böttiger C, Byrne RA, Steppich B, Koppara T, Gödel J, Hadamitzky M, Ott I, von Beckerath N, Kastrati A, Laugwitz KL, Ibrahim T.
Circ Cardiovasc Interv. 2014 Apr 1;7(2):207-15. doi: 10.1161/CIRCINTERVENTIONS.113.000836. Epub 2014 Apr 1.

Programmed Cell Death-1 Deficiency Exacerbates T Cell Activation and Atherogenesis despite Expansion of Regulatory T Cells in Atherosclerosis-Prone Mice.
Cochain C, Chaudhari SM, Koch M, Wiendl H, Eckstein HH, Zernecke A.
PLoS One. 2014 Apr 1;9(4):e93280. doi: 10.1371/journal.pone.0093280. eCollection 2014.

Fine tuning effector and regulatory T-cell dynamics: a novel tool for plaque regression?
Steffens S.
Cardiovasc Res. 2014 Apr 1;102(1):3-5. doi: 10.1093/cvr/cvu041. Epub 2014 Feb 20. No abstract available.

Rationale and design of The Intracoronary Stenting and Antithrombotic Regimen-Testing of a six-week versus a six-month clopidogrel treatment Regimen In Patients with concomitant aspirin and oraL anticoagulant therapy following drug-Eluting stenting (ISAR-TRIPLE) study.
Fiedler KA, Byrne RA, Schulz S, Sibbing D, Mehilli J, Ibrahim T, Maeng M, Laugwitz KL, Kastrati A, Sarafoff N.
Am Heart J. 2014 Apr;167(4):459-465.e1. doi: 10.1016/j.ahj.2014.01.005. Epub 2014 Jan 14.

The ABC of Thrombopoiesis.
Soehnlein O.
Arterioscler Thromb Vasc Biol. 2014 Apr;34(4):700-1. doi: 10.1161/ATVBAHA.114.303365. No abstract available.

Tracer kinetic modeling in myocardial perfusion quantification using MRI.
Schwab F, Ingrisch M, Marcus R, Bamberg F, Hildebrandt K, Adrion C, Gliemi C, Nikolaou K, Reiser M, Theisen D.
Magn Reson Med. 2014 Mar 31. doi: 10.1002/mrm.25212. [Epub ahead of print]

Coronary heart disease-associated variation in TCF21 disrupts a miR-224 binding site and miRNA-mediated regulation.
Miller CL, Haas U, Diaz R, Leeper NJ, Kundu RK, Patlolla B, Assimes TL, Kaiser FJ, Perisic L, Hedin U, Maegdefessel L, Schunkert H, Erdmann J, Quertermous T, Sczakiel G.
PLoS Genet. 2014 Mar 27;10(3):e1004263. doi: 10.1371/journal.pgen.1004263. eCollection 2014 Mar.

Atherogenic mononuclear cell recruitment is facilitated by oxidized lipoprotein-induced endothelial junctional adhesion molecule-A redistribution.
Schmitt MM, Fraemohs L, Hackeng TM, Weber C, Koenen RR.
Atherosclerosis. 2014 Mar 25;234(2):254-264. doi: 10.1016/j.atherosclerosis.2014.03.014. [Epub ahead of print]

lnduced pluripotent stem cell-derived cardiomyocytes for drug development and toxicity testing.
Sinnecker D, Laugwitz KL, Moretti A.
Pharmacol Ther. 2014 Mar 18. pii: S0163-7258(14)00065-5. doi: 10.1016/j.pharmthera.2014.03.004. [Epub ahead of print] Review.

Comparison of Prasugrel and Bivalirudin vs Clopidogrel and Heparin in Patients With ST-Segment Elevation Myocardial Infarction: Design and Rationale of the Bavarian Reperfusion Alternatives Evaluation (BRAVE) 4 Trial.
Schulz S, Richardt G, Laugwitz KL, Mehran R, Gershlick AH, Morath T, Mayer K, Neudecker J, Tölg R, Ibrahim T, Hauschke D, Braun D, Schunkert H, Kastrati A, Mehilli J; for the Bavarian Reperfusion Alternatives Evaluation (BRAVE) 4 Investigators.
Clin Cardiol. 2014 Mar 14. doi: 10.1002/clc.22268. [Epub ahead of print]

Neutrophils Cast NETs in Atherosclerosis: Employing Peptidylarginine Deiminase as a Therapeutic Target.
Döring Y, Soehnlein O, Weber C.
Circ Res. 2014 Mar 14;114(6):931-4. doi: 10.1161/CIRCRESAHA.114.303479. No abstract available.

Constitutive activation of PKA catalytic subunit in adrenal Cushing's syndrome.
Beuschlein F, Fassnacht M, Assié G, Calebiro D, Stratakis CA, Osswald A, Ronchi CL, Wieland T, Sbiera S, Faucz FR, Schaak K, Schmittfull A, Schwarzmayr T, Barreau O, Vezzosi D, Rizk-Rabin M, Zabel U, Szarek E, Salpea P, Forlino A, Vetro A, Zuffardi O, Kisker C, Diener S, Meitinger T, Lohse MJ, Reincke M, Bertherat J, Strom TM, Allolio B.
N Engl J Med. 2014 Mar 13;370(11):1019-28. doi: 10.1056/NEJMoa1310359. Epub 2014 Feb 26.


Randomised, double-blind trial on the value of tapered discontinuation of clopidogrel maintenance therapy after drug-eluting stent implantation. Intracoronary Stenting and Antithrombotic Regimen: CAUTION in Discontinuing Clopidogrel Therapy - ISAR-CAUTION.
Fiedler KA, Mehilli J, Kufner S, Schlichting A, Ibrahim T, Sibbing D, Ott I, Schunkert H, Laugwitz KL, Kastrati A, Schulz S.
Thromb Haemost. 2014 Mar 13;111(6). [Epub ahead of print]

MicroRNA-126-5p promotes endothelial proliferation and limits atherosclerosis by suppressing Dlk1.
Schober A, Nazari-Jahantigh M, Wei Y, Bidzhekov K, Gremse F, Grommes J, Megens RT, Heyll K, Noels H, Hristov M, Wang S, Kiessling F, Olson EN, Weber C.
Nat Med. 2014 Mar 2. doi: 10.1038/nm.3487. [Epub ahead of print]

Current Treatment of In-Stent Restenosis.
Alfonso F, Byrne RA, Rivero F, Kastrati A.
J Am Coll Cardiol. 2014 Mar 1. pii: S0735-1097(14)01354-0. doi: 10.1016/j.jacc.2014.02.545. [Epub ahead of print] Review.

Sirolimus-eluting versus paclitaxel-eluting stents in diabetic and non-diabetic patients within sirolimus-eluting stent restenosis: Results from the ISAR-DESIRE 2 trial.
Kufner S, Byrne RA, de Waha A, Schulz S, Joner M, Laugwitz KL, Kastrati A; Intracoronary Stenting and Angiographic Results: Drug Eluting Stents for In-Stent Restenosis 2, (ISAR-DESIRE 2) Investigators.
Cardiovasc Revasc Med. 2014 Mar;15(2):69-75. doi: 10.1016/j.carrev.2014.02.001. Epub 2014 Feb 15.

Automated analysis of contractile force and Ca2+ transients in engineered heart tissue.
Stoehr A, Neuber C, Baldauf C, Vollert I, Friedrich FW, Flenner F, Carrier L, Eder A, Schaaf S, Hirt MN, Aksehirlioglu B, Tong CW, Moretti A, Eschenhagen T, Hansen A.
Am J Physiol Heart Circ Physiol. 2014 Feb 28. [Epub ahead of print]

Rubbing salt into wounded endothelium: Sodium potentiates proatherogenic effects of TNF-α under non-uniform shear stress.
Wild J, Soehnlein O, Dietel B, Urschel K, Garlichs CD, Cicha I.
Thromb Haemost. 2014 Feb 27;112(1). [Epub ahead of print]

Feasibility of dynamic CT-based adenosine stress myocardial perfusion imaging to detect and differentiate ischemic and infarcted myocardium in an large experimental porcine animal model.
Bamberg F, Hinkel R, Marcus RP, Baloch E, Hildebrandt K, Schwarz F, Hetterich H, Sandner TA, Schlett CL, Ebersberger U, Kupatt C, Hoffmann U, Reiser MF, Theisen D, Nikolaou K.
Int J Cardiovasc Imaging. 2014 Feb 26. [Epub ahead of print]

The effects of oral hydrolytic enzymes and flavonoids on inflammatory markers and coagulation after marathon running: study protocol for a randomized, double-blind, placebo-controlled trial.
Grabs V, Nieman DC, Haller B, Halle M, Scherr J.
BMC Sports Sci Med Rehabil. 2014 Feb 22;6(1):8. doi: 10.1186/2052-1847-6-8.

Nocturnal Respiratory Rate Predicts Non-Sudden Cardiac Death in Survivors of Acute Myocardial Infarction.
Dommasch M, Sinnecker D, Barthel P, Müller A, Dirschinger RJ, Hapfelmeier A, Huster KM, Laugwitz KL, Malik M, Schmidt G.
J Am Coll Cardiol. 2014 Feb 21. pii: S0735-1097(14)01148-6. doi: 10.1016/j.jacc.2014.02.525. [Epub ahead of print] No abstract available.

Inhibition of Cullin-RING E3 ubiquitin ligase 7 by simian virus 40 large T antigen.
Hartmann T, Xu X, Kronast M, Muehlich S, Meyer K, Zimmermann W, Hurwitz J, Pan ZQ, Engelhardt S, Sarikas A.
Proc Natl Acad Sci U S A. 2014 Feb 18. [Epub ahead of print]

Blocking CD40-TRAF6 signaling is a therapeutic target in obesity-associated insulin resistance.
Chatzigeorgiou A, Seijkens T, Zarzycka B, Engel D, Poggi M, van den Berg S, van den Berg S, Soehnlein O, Winkels H, Beckers L, Lievens D, Driessen A, Kusters P, Biessen E, Garcia-Martin R, Klotzsche-von Ameln A, Gijbels M, Noelle R, Boon L, Hackeng T, Schulte K, Xu A, Vriend G, Nabuurs S, Chung KJ, Willems van Dijk K, Rensen PC, Gerdes N, de Winther M, Block NL, Schally AV, Weber C, Bornstein SR, Nicolaes G, Chavakis T, Lutgens E.
Proc Natl Acad Sci U S A. 2014 Feb 18;111(7):2686-91. doi: 10.1073/pnas.1400419111. Epub 2014 Feb 3.

VEGF-B: a more balanced approach toward cardiac neovascularization?
Kupatt C, Hinkel R.
EMBO Mol Med. 2014 Feb 12. [Epub ahead of print] No abstract available.

Controlled intramyocardial release of engineered chemokines by biodegradable hydrogels as a treatment approach of myocardial infarction.
Projahn D, Simsekyilmaz S, Singh S, Kanzler I, Kramp BK, Langer M, Burlacu A, Bernhagen J, Klee D, Zernecke A, Hackeng TM, Groll J, Weber C, Liehn EA, Koenen RR.
J Cell Mol Med. 2014 Feb 6. doi: 10.1111/jcmm.12225. [Epub ahead of print]

Microvascular dysfunction in the course of metabolic syndrome induced by high-fat diet.
Aoqui C, Chmielewski S, Scherer E, Eissler R, Sollinger D, Heid I, Braren R, Schmaderer C, Megens RT, Weber C, Heemann U, Tschöp M, Baumann M.
Cardiovasc Diabetol. 2014 Feb 3;13:31. doi: 10.1186/1475-2840-13-31.

Bone marrow-specific knock-in of a non-activatable ikkα kinase mutant influences haematopoiesis but not atherosclerosis in apoe-deficient mice.
Tilstam PV, Gijbels MJ, Habbeddine M, Cudejko C, Asare Y, Theelen W, Zhou B, Döring Y, Drechsler M, Pawig L, Simsekyilmaz S, Koenen RR, de Winther MP, Lawrence T, Bernhagen J, Zernecke A, Weber C, Noels H.
PLoS One. 2014 Feb 3;9(2):e87452. doi: 10.1371/journal.pone.0087452. eCollection 2014.

Strengths and Weaknesses of a New Mouse Model of Thrombosis Induced by Inferior Vena Cava Stenosis.
Geddings JE, Aleman MM, Wolberg AS, von Brϋhl ML, Massberg S, Mackman N.
J Thromb Haemost. 2014 Jan 26. doi: 10.1111/jth.12510. [Epub ahead of print]

[Genetic analyses as basis for a personalized medicine in patients with coronary artery disease.]
Kessler T, Kaess B, Bourier F, Erdmann J, Schunkert H.
Herz. 2014 Jan 26. [Epub ahead of print] German.

Nanomedicine-based strategies for treatment of atherosclerosis.
Schiener M, Hossann M, Viola JR, Ortega-Gomez A, Weber C, Lauber K, Lindner LH, Soehnlein O.
Trends Mol Med. 2014 Jan 25. pii: S1471-4914(13)00211-6. doi: 10.1016/j.molmed.2013.12.001. [Epub ahead of print]

Novel Genetic Markers Associate with Atrial Fibrillation Risk in Europeans and Japanese.
Lubitz SA, Lunetta KL, Lin H, Arking DE, Trompet S, Li G, Krijthe BP, Chasman DI, Barnard J, Kleber ME, Dörr M, Ozaki K, Smith AV, Müller-Nurasyid M, Walter S, Agarwal SK, Bis JC, Brody JA, Chen LY, Everett BM, Ford I, Franco OH, Harris TB, Hofman A, Kääb S, Mahida S, Kathiresan S, Kubo M, Launer LJ, Macfarlane PW, Magnani JW, McKnight B, McManus DD, Peters A, Psaty BM, Rose LM, Rotter JI, Silbernagel G, Smith JD, Sotoodehnia N, Stott DJ, Taylor KD, Tomaschitz A, Tsunoda T, Uitterlinden AG, Van Wagoner DR, Völker U, Völzke H, Murabito JM, Sinner MF, Gudnason V, Felix SB, März W, Chung M, Albert CM, Stricker BH, Tanaka T, Heckbert SR, Jukema JW, Alonso A, Benjamin EJ, Ellinor PT.
J Am Coll Cardiol. 2014 Jan 17. pii: S0735-1097(14)00171-5. doi: 10.1016/j.jacc.2013.12.015. [Epub ahead of print]

Common Variation in Fatty Acid Metabolic Genes and Risk of Incident Sudden Cardiac Arrest.
Lemaitre RN, Johnson CO, Hesselson S, Sotoodhenia N, McKnight B, Sitlani CM, Rea TD, King IB, Kwok PY, Mak A, Li G, Brody J, Larson E, Mozaffarian D, Psaty BM, Huertas-Vazquez A, Tardif JC, Albert CM, Lyytikäinen LP, Arking DE, Kääb S, Huikuri HV, Krijthe BP, Eijgelsheim M, Wang YA, Reinier K, Lehtimäki T, Pulit SL, Brugada R, Müller-Nurasyid M, Newton-Cheh CH, Karhunen PJ, Stricker BH, Goyette P, Rotter JI, Chugh SS, Chakravarti A, Jouven X, Siscovick DS.
Heart Rhythm. 2014 Jan 10. pii: S1547-5271(14)00010-1. doi: 10.1016/j.hrthm.2014.01.008. [Epub ahead of print]

Atherosclerotic plaque destabilization: mechanisms, models, and therapeutic strategies.
Silvestre-Roig C, de Winther MP, Weber C
, Daemen MJ, Lutgens E, Soehnlein O.
Circ Res. 2014 Jan 3;114(1):214-26. doi: 10.1161/CIRCRESAHA.114.302355.

Metabolite profiling reveals new insights into the regulation of serum urate in humans.
Albrecht E, Waldenberger M, Krumsiek J, Evans AM, Jeratsch U, Breier M, Adamski J, Koenig W, Zeilinger S, Fuchs C, Klopp N, Theis FJ, Wichmann HE, Suhre K, Illig T, Strauch K, Peters A, Gieger C, Kastenmüller G, Doering A, Meisinger C.
Metabolomics. 2014;10:141-151. Epub 2013 Jul 20.

Randomized Comparison of Ticagrelor versus Prasugrel in Patients with Acute Coronary Syndrome and Planned Invasive Strategy-Design and Rationale of the Intracoronary Stenting and Antithrombotic Regimen: Rapid Early Action for Coronary Treatment (ISAR-REACT) 5 Trial.
Schulz S, Angiolillo DJ, Antoniucci D, Bernlochner I, Hamm C, Jaitner J, Laugwitz KL, Mayer K, von Merzljak B, Morath T, Neumann FJ, Richardt G, Ruf J, Schömig G, Schühlen H, Schunkert H, Kastrati A
; Intracoronary Stenting and Antithrombotic Regimen: Rapid Early Action for Coronary Treatment (ISAR-REACT) 5 Trial Investigators.
J Cardiovasc Transl Res. 2013 Dec 27. [Epub ahead of print]

Activation of CXCR7 Limits Atherosclerosis and Improves Hyperlipidemia by Increasing Cholesterol Uptake in Adipose Tissue.
Li X, Zhu M, Penfold ME, Koenen RR, Thiemann A, Heyll K, Akhtar S, Koyadan S, Wu Z, Gremse F, Kiessling F, van Zandvoort M, Schall TJ, Weber C
, Schober A.
Circulation. 2013 Dec 27. [Epub ahead of print]

Fractalkine promotes platelet activation and vascular dysfunction in congestive heart failure.
Hildemann SK, Schulz C, Fraccarollo D, Schöpp C, Flierl U, Wissel K, Pelisek J, Massberg S
, Bauersachs J, Schäfer A.
Thromb Haemost. 2013 Dec 12;111(4). [Epub ahead of print]

Percutaneous edge-to-edge repair of the mitral valve in patients with degenerative versus functional mitral regurgitation.
Braun D, Lesevic H, Orban M, Michalk F, Barthel P, Hoppe K, Sonne C, Pache J, Mehilli J, Kastrati A, Hausleiter J, Massberg S.
Catheter Cardiovasc Interv. 2013 Dec 10. doi: 10.1002/ccd.25331. [Epub ahead of print]

Impact of Coronary Anatomy and Stenting Technique on Long-Term Outcome After Drug-Eluting Stent Implantation for Unprotected Left Main Coronary Artery Disease.
Tiroch K, Mehilli J, Byrne RA, Schulz S, Massberg S, Laugwitz KL, Vorpahl M, Seyfarth M, Kastrati A; for the Intracoronary Stenting and Angiographic Results: Drug-Eluting Stents for Unprotected Coronary Left Main Lesions (ISAR-LEFT MAIN) Study Investigators.
JACC Cardiovasc Interv. 2013 Dec 5. pii: S1936-8798(13)01542-2. doi: 10.1016/j.jcin.2013.08.013. [Epub ahead of print]

Telomere length in circulating leukocytes is associated with lung function and disease.
Albrecht E, Sillanpää E, Karrasch S, Alves AC, Codd V, Hovatta I, Buxton JL, Nelson CP, Broer L, Hägg S, Mangino M, Willemsen G, Surakka I, Ferreira MA, Amin N, Oostra BA, Bäckmand HM, Peltonen M, Sarna S, Rantanen T, Sipilä S, Korhonen T, Madden PA, Gieger C, Jörres RA, Heinrich J, Behr J, Huber RM, Peters A, Strauch K, Wichmann HE, Waldenberger M, Blakemore AI, de Geus EJ, Nyholt DR, Henders AK, Piirilä PL, Rissanen A, Magnusson PK, Viñuela A, Pietiläinen KH, Martin NG, Pedersen NL, Boomsma DI, Spector TD, van Duijn CM, Kaprio J, Samani NJ, Jarvelin MR, Schulz H.
Eur Respir J. 2013 Dec 5. [Epub ahead of print]

Association of leptin and insulin with childhood obesity and retinal vessel diameters.
Siegrist M, Hanssen H, Neidig M, Fuchs M, Lechner F, Stetten M, Blume K, Lammel C, Haller B, Vogeser M, Parhofer KG, Halle M
.
Int J Obes (Lond). 2013 Dec 4. doi: 10.1038/ijo.2013.226. [Epub ahead of print]

Coinciding functions for miR-145 in vascular smooth muscle and cardiac fibroblasts.
Engelhardt S, Leierseder S.
J Mol Cell Cardiol. 2013 Dec;65:105-7. doi: 10.1016/j.yjmcc.2013.10.002. Epub 2013 Oct 17. No abstract available.

[Ventricular tachycardia : Treatment and prognostic significance].
Fichtner S, Kääb S.
Herzschrittmacherther Elektrophysiol. 2013 Dec;24(4):217-22. doi: 10.1007/s00399-013-0296-0. German.

Drug-eluting stents for revascularization of infrapopliteal arteries: updated meta-analysis of randomized trials.
Fusaro M, Cassese S, Ndrepepa G, Tepe G, King L, Ott I, Nerad M, Schunkert H, Kastrati A
.
JACC Cardiovasc Interv. 2013 Dec;6(12):1284-93. doi: 10.1016/j.jcin.2013.08.007.

Risk of stent thrombosis among bare-metal stents, first-generation drug-eluting stents, and second-generation drug-eluting stents: results from a registry of 18,334 patients.
Tada T, Byrne RA, Simunovic I, King LA, Cassese S, Joner M, Fusaro M, Schneider S, Schulz S, Ibrahim T, Ott I, Massberg S, Laugwitz KL, Kastrati A
.
JACC Cardiovasc Interv. 2013 Dec;6(12):1267-74. doi: 10.1016/j.jcin.2013.06.015.

Incidence and predictors of restenosis after coronary stenting in 10 004 patients with surveillance angiography.
Cassese S, Byrne RA, Tada T, Pinieck S, Joner M, Ibrahim T, King LA, Fusaro M, Laugwitz KL, Kastrati A.
Heart. 2013 Nov 22. doi: 10.1136/heartjnl-2013-304933. [Epub ahead of print]

Evaluation of the prevalence and prospective clinical impact of the JAK2 V617F mutation in coronary patients.
Muendlein A, Gasser K, Kinz E, Stark N, Leiherer A, Rein P, Saely CH, Grallert H, Peters A, Drexel H, Lang AH.
Am J Hematol. 2013 Nov 22. doi: 10.1002/ajh.23632. [Epub ahead of print]

β-Catenin-dependent pathway activation by both promiscuous "canonical" WNT3a-, and specific "noncanonical" WNT4- and WNT5a-FZD receptor combinations with strong differences in LRP5 and LRP6 dependency.
Ring L, Neth P, Weber C, Steffens S, Faussner A.
Cell Signal. 2013 Nov 21. doi:pii: S0898-6568(13)00352-5. 10.1016/j.cellsig.2013.11.021. [Epub ahead of print]

Shared Genetic Susceptibility to Ischemic Stroke and Coronary Artery Disease: A Genome-Wide Analysis of Common Variants.
Dichgans M, Malik R, König IR, Rosand J, Clarke R, Gretarsdottir S, Thorleifsson G, Mitchell BD, Assimes TL, Levi C, Odonnell CJ, Fornage M, Thorsteinsdottir U, Psaty BM, Hengstenberg C, Seshadri S, Erdmann J, Bis JC, Peters A, Boncoraglio GB, März W, Meschia JF, Kathiresan S, Ikram MA, McPherson R, Stefansson K, Sudlow C, Reilly MP, Thompson JR, Sharma P, Hopewell JC, Chambers JC, Watkins H, Rothwell PM, Roberts R, Markus HS, Samani NJ, Farrall M, Schunkert H; the METASTROKE Consortium; the CARDIoGRAM consortium; the C4D consortium; the International Stroke Genetics Consortium; Collaborators/second tier of authors.
Stroke. 2013 Nov 21. [Epub ahead of print]

Platelet-derived PF4 reduces neutrophil apoptosis following arterial occlusion.
Hartwig H, Drechsler M, Lievens D, Kramp B, von Hundelshausen P, Lutgens E, Weber C, Döring Y, Soehnlein O.
Thromb Haemost. 2013 Nov 21;111(3). [Epub ahead of print] No abstract available.

Targeted sequencing in candidate genes for atrial fibrillation: the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Targeted Sequencing Study.
Lin H, Sinner MF, Brody JA, Arking DE, Lunetta KL, Rienstra M, Lubitz SA, Magnani JW, Sotoodehnia N, McKnight B, McManus DD, Boerwinkle E, Psaty BM, Rotter JI, Bis JC, Gibbs RA, Muzny D, Kovar CL, Morrison AC, Gupta M, Folsom AR, Kääb S, Heckbert SR, Alonso A, Ellinor PT, Benjamin EJ; on behalf of the CHARGE Atrial Fibrillation Working Group.
Heart Rhythm. 2013 Nov 14. doi:pii: S1547-5271(13)01316-7. 10.1016/j.hrthm.2013.11.012. [Epub ahead of print]

Sick Sinus Syndrome in HCN1-Deficient Mice.
Fenske S, Krause SC, Hassan SI, Becirovic E, Auer F, Bernard R, Kupatt C, Lange P, Ziegler T, Wotjak CT, Zhang H, Hammelmann V, Paparizos C, Biel M, Wahl-Schott CA.
Circulation. 2013 Nov 11. [Epub ahead of print]

Dysfunctional nitric oxide signalling increases risk of myocardial infarction.
Erdmann J, Stark K, Esslinger UB, Rumpf PM, Koesling D, de Wit C, Kaiser FJ, Braunholz D, Medack A, Fischer M, Zimmermann ME, Tennstedt S, Graf E, Eck S, Aherrahrou Z, Nahrstaedt J, Willenborg C, Bruse P, Brænne I, Nöthen MM, Hofmann P, Braund PS, Mergia E, Reinhard W, Burgdorf C, Schreiber S, Balmforth AJ, Hall AS, Bertram L, Steinhagen-Thiessen E, Li SC, März W, Reilly M, Kathiresan S, McPherson R, Walter U, Cardiogram, Ott J, Samani NJ, Strom TM, Meitinger T, Hengstenberg C, Schunkert H.
Nature. 2013 Nov 10. doi: 10.1038/nature12722. [Epub ahead of print]

Evidence for a regulatory role of Cullin-RING E3 ubiquitin ligase 7 in insulin signaling.
Scheufele F, Wolf B, Kruse M, Hartmann T, Lempart J, Mühlich S, Pfeiffer AF, Field LJ, Charron MJ, Pan ZQ, Engelhardt S, Sarikas A.
Cell Signal. 2013 Nov 9. doi:pii: S0898-6568(13)00326-4. 10.1016/j.cellsig.2013.11.005. [Epub ahead of print]

Isogenic human pluripotent stem cell pairs reveal the role of a KCNH2 mutation in long-QT syndrome.
Bellin M, Casini S, Davis RP, D'Aniello C, Haas J, Ward-van Oostwaard D, Tertoolen LG, Jung CB, Elliott DA, Welling A, Laugwitz KL, Moretti A, Mummery CL.
EMBO J. 2013 Nov 8. doi: 10.1038/emboj.2013.240. [Epub ahead of print]

The Role of Extracellular RNA in Atherosclerotic Plaque Formation in Mice.
Simsekyilmaz S, Cabrera-Fuentes HA, Meiler S, Kostin S, Baumer Y, Liehn EA, Weber C, Boisvert WA, Preissner KT, Zernecke A.
Circulation. 2013 Nov 7. [Epub ahead of print]

Genome wide analysis of drug-induced torsades de pointes: lack of common variants with large effect sizes.
Behr ER, Ritchie MD, Tanaka T, Kääb S, Crawford DC, Nicoletti P, Floratos A, Sinner MF, Kannankeril PJ, Wilde AA, Bezzina CR, Schulze-Bahr E, Zumhagen S, Guicheney P, Bishopric NH, Marshall V, Shakir S, Dalageorgou C, Bevan S, Jamshidi Y, Bastiaenen R, Myerburg RJ, Schott JJ, Camm AJ, Steinbeck G, Norris K, Altman RB, Tatonetti NP, Jeffery S, Kubo M, Nakamura Y, Shen Y, George AL Jr, Roden DM.
PLoS One. 2013 Nov 6;8(11):e78511. doi: 10.1371/journal.pone.0078511.

Pluripotent stem cell models of human heart disease.
Moretti A, Laugwitz KL, Dorn T, Sinnecker D, Mummery C.
Cold Spring Harb Perspect Med. 2013 Nov 1;3(11). doi:pii: a014027. 10.1101/cshperspect.a014027.

Mutational analysis of the human MESP1 gene in patients with congenital heart disease reveals a highly variable sequence in exon 1.
Lahm H, Deutsch MA, Dreßen M, Doppler S, Werner A, Hörer J, Cleuziou J, Schreiber C, Böhm J, Laugwitz KL, Lange R, Krane M.
Eur J Med Genet. 2013 Nov;56(11):591-8. doi: 10.1016/j.ejmg.2013.09.001. Epub 2013 Sep 19.

Drug-eluting stent trials: too much non-inferiority, too little progress?
Byrne RA, Kastrati A.
Lancet. 2013 Oct 31. doi:pii: S0140-6736(13)62240-0. 10.1016/S0140-6736(13)62240-0. [Epub ahead of print]

Health-Related Quality of Life and Functional Outcome in Cardiac Surgical Patients Aged 80 Years and Older: A Prospective Single Center Study.
Deutsch MA, Krane M, Schneider L, Wottke M, Kornek M, Elhmidi Y, Badiu CC, Bleiziffer S, Voss B, Lange R.
J Card Surg. 2013 Oct 23. doi: 10.1111/jocs.12233. [Epub ahead of print]

Myocardial CT Perfusion Imaging in a Large Animal Model: Comparison of Dynamic Versus Single-Phase Acquisitions.
Schwarz F, Hinkel R, Baloch E, Marcus RP, Hildebrandt K, Sandner TA, Kupatt C, Hoffmann V, Wintersperger BJ, Reiser MF, Theisen D, Nikolaou K, Bamberg F.
JACC Cardiovasc Imaging. 2013 Oct 17. doi:pii: S1936-878X(13)00667-0. 10.1016/j.jcmg.2013.05.018. [Epub ahead of print]

β1 integrin-mediated signals are required for platelet granule secretion and hemostasis in mouse.
Petzold T, Ruppert R, Pandey D, Barocke V, Meyer H, Lorenz M, Zhang L, Siess W, Massberg S, Moser M.
Blood. 2013 Oct 10;122(15):2723-31. doi: 10.1182/blood-2013-06-508721. Epub 2013 Sep 4.

CCR6 selectively promotes monocyte mediated inflammation and atherogenesis in mice.
Manthey HD, Cochain C, Barnsteiner S, Karshovska E, Pelisek J, Koch M, Chaudhari SM, Busch M, Eckstein HH, Weber C, Koenen RR, Zernecke A.
Thromb Haemost. 2013 Oct 10;110(6). [Epub ahead of print]

Novel role of mechanosensitive AT1B receptors in myogenic vasoconstriction.
Blodow S, Schneider H, Storch U, Wizemann R, Forst AL, Gudermann T, Mederos Y Schnitzler M.
Pflugers Arch. 2013 Oct 8. [Epub ahead of print]

Impact of real-time contact force and impedance measurement in pulmonary vein isolation procedures for treatment of atrial fibrillation.
Wakili R, Clauss S, Schmidt V, Ulbrich M, Hahnefeld A, Schüssler F, Siebermair J, Kääb S, Estner HL.
Clin Res Cardiol. 2013 Oct 6. [Epub ahead of print]

Incidence and impact on prognosis of bleeding during percutaneous coronary interventions in patients with chronic kidney disease.
Ndrepepa G, Neumann FJ, Cassese S, Fusaro M, Ott I, Schulz S, Hoppmann P, Richardt G, Laugwitz KL, Schunkert H, Kastrati A.
Clin Res Cardiol. 2013 Oct 4. [Epub ahead of print]

Intravenous β-Blockers in Primary Percutaneous Coronary Intervention: New Hope for an Old Therapy.
Ndrepepa G, Kastrati A.
Circulation. 2013 Oct 1;128(14):1487-9. doi: 10.1161/CIRCULATIONAHA.113.005500. Epub 2013 Sep 3. No abstract

Embryonic heart progenitors and cardiogenesis.
Brade T, Pane LS, Moretti A, Chien KR, Laugwitz KL.
Cold Spring Harb Perspect Med. 2013 Oct 1;3(10). doi:pii: a013847. 10.1101/cshperspect.a013847.available.

Systematic identification of trans eQTLs as putative drivers of known disease associations.
Westra HJ, Peters MJ, Esko T, Yaghootkar H, Schurmann C, Kettunen J, Christiansen MW, Fairfax BP, Schramm K, Powell JE, Zhernakova A, Zhernakova DV, Veldink JH, Van den Berg LH, Karjalainen J, Withoff S, Uitterlinden AG, Hofman A, Rivadeneira F, 't Hoen PA, Reinmaa E, Fischer K, Nelis M, Milani L, Melzer D, Ferrucci L, Singleton AB, Hernandez DG, Nalls MA, Homuth G, Nauck M, Radke D, Völker U, Perola M, Salomaa V, Brody J, Suchy-Dicey A, Gharib SA, Enquobahrie DA, Lumley T, Montgomery GW, Makino S, Prokisch H, Herder C, Roden M, Grallert H, Meitinger T, Strauch K, Li Y, Jansen RC, Visscher PM, Knight JC, Psaty BM, Ripatti S, Teumer A, Frayling TM, Metspalu A, van Meurs JB, Franke L.
Nat Genet. 2013 Oct;45(10):1238-43. doi: 10.1038/ng.2756. Epub 2013 Sep 8.

microRNA-22 Promotes Heart Failure through Coordinate Suppression of PPAR/ERR-Nuclear Hormone Receptor Transcription.
Gurha P, Wang T, Larimore AH, Sassi Y, Abreu-Goodger C, Ramirez MO, Reddy AK, Engelhardt S, Taffet GE, Wehrens XH, Entman ML, Rodriguez A.
PLoS One. 2013 Sep 27;8(9):e75882. doi: 10.1371/journal.pone.0075882.

Transcriptome and genome sequencing uncovers functional variation in humans.
Lappalainen T, Sammeth M, Friedländer MR, 't Hoen PA, Monlong J, Rivas MA, Gonzàlez-Porta M, Kurbatova N, Griebel T, Ferreira PG, Barann M, Wieland T, Greger L, van Iterson M, Almlöf J, Ribeca P, Pulyakhina I, Esser D, Giger T, Tikhonov A, Sultan M, Bertier G, MacArthur DG, Lek M, Lizano E, Buermans HP, Padioleau I, Schwarzmayr T, Karlberg O, Ongen H, Kilpinen H, Beltran S, Gut M, Kahlem K, Amstislavskiy V, Stegle O, Pirinen M, Montgomery SB, Donnelly P, McCarthy MI, Flicek P, Strom TM; Geuvadis Consortium, Lehrach H, Schreiber S, Sudbrak R, Carracedo A, Antonarakis SE, Häsler R, Syvänen AC, van Ommen GJ, Brazma A, Meitinger T, Rosenstiel P, Guigó R, Gut IG, Estivill X, Dermitzakis ET, Palotie A, Deleuze JF, Gyllensten U, Brunner H, Veltman J, Cambon-Thomsen A, Mangion J, Bentley D, Hamosh A.
Nature. 2013 Sep 26;501(7468):506-11. doi: 10.1038/nature12531. Epub 2013 Sep 15.

MiR-223 is dispensable for platelet production and function in mice.
Leierseder S, Petzold T, Zhang L, Loyer X, Massberg S, Engelhardt S.
Thromb Haemost. 2013 Sep 26;110(6). [Epub ahead of print]

Exome Sequencing and Directed Clinical Phenotyping Diagnose Cholesterol Ester Storage Disease Presenting as Autosomal Recessive Hypercholesterolemia.
Stitziel NO, Fouchier SW, Sjouke B, Peloso GM, Moscoso AM, Auer PL, Goel A, Gigante B, Barnes TA, Melander O, Orho-Melander M, Duga S, Sivapalaratnam S, Nikpay M, Martinelli N, Girelli D, Jackson RD, Kooperberg C, Lange LA, Ardissino D, McPherson R, Farrall M, Watkins H, Reilly MP, Rader DJ, de Faire U, Schunkert H, Erdmann J, Samani NJ, Charnas L, Altshuler D, Gabriel S, Kastelein JJ, Defesche JC, Nederveen AJ, Kathiresan S, Hovingh GK; for the National Heart, Lung, and Blood Institute GO Exome Sequencing Project.
Arterioscler Thromb Vasc Biol. 2013 Sep 26. [Epub ahead of print]

Endothelial JAM-A Guides Monocytes into Flow-Dependent Predilection Sites of Atherosclerosis.
Schmitt MM, Megens RT, Zernecke A, Bidzhekov K, van den Akker NM, Rademakers T, van Zandvoort MA, Hackeng TM, Koenen RR, Weber C.
Circulation. 2013 Sep 24. [Epub ahead of print]

Apolipoprotein E genotype, TNF-α 308G/A and risk for cardiac surgery associated-acute kidney injury in Caucasians.
Boehm J, Eichhorn S, Kornek M, Hauner K, Prinzing A, Grammer J, Lahm H, Wagenpfeil S, Lange R.
Ren Fail. 2013 Sep 24. [Epub ahead of print]

Incidence and prognostic value of bleeding after percutaneous coronary intervention in patients older than 75 years of age.
Ndrepepa G, Neumann FJ, Schulz S, Fusaro M, Cassese S, Byrne RA, Richardt G, Laugwitz KL, Kastrati A.
Catheter Cardiovasc Interv. 2013 Sep 13. doi: 10.1002/ccd.25189. [Epub ahead of print]

Rhodamine-loaded ICAM-targeted Microbubbles for Dual-modality Imaging Under Controlled Shear Stresses.
Wu Z, Curaj A, Fokong S, Liehn EA, Weber C, Lammers T, Kiessling F, van Zandvoort M.
Circ Cardiovasc Imaging. 2013 Sep 13. [Epub ahead of print]

High-pitch coronary CT angiography in dual-source CT during free breathing vs. breath holding in patients with low heart rates.
Bischoff B, Meinel FG, Del Prete A, Reiser MF, Becker HC.
Eur J Radiol. 2013 Sep 12. doi:pii: S0720-048X(13)00482-8. 10.1016/j.ejrad.2013.09.003. [Epub ahead of print]

Compartmentalized Protective and Detrimental Effects of Endogenous Macrophage Migration-Inhibitory Factor Mediated by CXCR2 in a Mouse Model of Myocardial Ischemia/Reperfusion.
Liehn EA, Kanzler I, Konschalla S, Kroh A, Simsekyilmaz S, Sönmez TT, Bucala R, Bernhagen J, Weber C
.
Arterioscler Thromb Vasc Biol. 2013 Sep;33(9):2180-2186. Epub 2013 Jul 18.

Bleeding after percutaneous coronary intervention in women and men matched for age, body mass index, and type of antithrombotic therapy.
Ndrepepa G, Schulz S, Neumann FJ, Byrne RA, Hoppmann P, Cassese S, Ott I, Fusaro M, Ibrahim T, Tada T, Richardt G, Laugwitz KL, Schunkert H, Kastrati A.
Am Heart J. 2013 Sep;166(3):534-40. doi: 10.1016/j.ahj.2013.07.006. Epub 2013 Aug 6.

[Chronic inflammation and atherosclerosis].
von Hundelshausen P, Weber C.
Dtsch Med Wochenschr. 2013 Sep;138(37):1839-44. doi: 10.1055/s-0033-1349426. Epub 2013 Sep 4. German.

Unmet Aspirations - Where To Now for Catheter Thrombectomy?
Byrne RA, Kastrati A.
N Engl J Med. 2013 Aug 31. [Epub ahead of print]

Functional expression of the transient receptor potential channel TRPA1, a sensor for toxic lung inhalants, in pulmonary epithelial cells.
Büch TR, Schäfer EA, Demmel MT, Boekhoff I, Thiermann H, Gudermann T, Steinritz D, Schmidt A.
Chem Biol Interact. 2013 Aug 30. doi:pii: S0009-2797(13)00220-2. 10.1016/j.cbi.2013.08.012. [Epub ahead of print]

A regulatory variant in CCR6 is associated with anti-topoisomerase positive systemic sclerosis susceptibility.
Koumakis E, Bouaziz M, Dieudé P, Ruiz B, Riemekasten G, Airo P, Müller-Nurasyid M, Cusi D, Matucci-Cerinic M, Melchers I, Salvi E, Strauch K, Peters A, Cuomo G, Hachulla E, Diot E, Hunzelmann N, Caramaschi P, Riccieri V, Distler JH, Tarner I, Avouac J, Letenneur L, Amouyel P, Lambert JC, Chiocchia G, Boileau C, Allanore Y.
Arthritis Rheum. 2013 Aug 27. doi: 10.1002/art.38136. [Epub ahead of print]


Exchange of extracellular domains of CCR1 and CCR5 reveals confined functions in CCL5-mediated cell recruitment.
Kramp BK, Megens RT, Sarabi A, Winkler S, Projahn D, Weber C
, Koenen RR, von Hundelshausen P.
Thromb Haemost. 2013 Aug 8;110(4). [Epub ahead of print]

Combined deficiency in glutathione peroxidase 4 and vitamin E causes multiorgan thrombus formation and early death in mice.
Wortmann M, Schneider M, Pircher J, Hellfritsch J, Aichler M, Vegi N, Kölle P, Kuhlencordt P, Walch A, Pohl U, Bornkamm GW, Conrad M, Beck H.
Circ Res. 2013 Aug 2;113(4):408-17. doi: 10.1161/CIRCRESAHA.113.279984. Epub 2013 Jun 14.

Sphingosine kinase 2 (Sphk2) regulates platelet biogenesis by providing intracellular sphingosine 1-phosphate (S1P).
Zhang L, Urtz N, Gaertner F, Legate KR, Petzold T, Lorenz M, Mazharian A, Watson SP, Massberg S.
Blood. 2013 Aug 1;122(5):791-802. doi: 10.1182/blood-2012-12-473884. Epub 2013 Jun 17.

Prognostic value of access and non-access sites bleeding after percutaneous coronary intervention.
Ndrepepa G, Neumann FJ, Richardt G, Schulz S, Tölg R, Stoyanov KM, Gick M, Ibrahim T, Fiedler KA, Berger PB, Laugwitz KL, Kastrati A.
Circ Cardiovasc Interv. 2013 Aug;6(4):354-61. doi: 10.1161/CIRCINTERVENTIONS.113.000433. Epub 2013 Jul 23.

Inhibition of MicroRNA-92a Protects Against Ischemia-Reperfusion Injury in a Large Animal Model.
Hinkel R, Penzkofer D, Zühlke S, Fischer A, Husada W, Xu QF, Baloch E, van Rooij E, Zeiher AM, Kupatt C
, Dimmeler S.
Circulation. 2013 Jul 29. [Epub ahead of print]

Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death.
Bezzina CR, Barc J, Mizusawa Y, Remme CA, Gourraud JB, Simonet F, Verkerk AO, Schwartz PJ, Crotti L, Dagradi F, Guicheney P, Fressart V, Leenhardt A, Antzelevitch C, Bartkowiak S, Schulze-Bahr E, Zumhagen S, Behr ER, Bastiaenen R, Tfelt-Hansen J, Olesen MS, Kääb S, Beckmann BM, Weeke P, Watanabe H, Endo N, Minamino T, Horie M, Ohno S, Hasegawa K, Makita N, Nogami A, Shimizu W, Aiba T, Froguel P, Balkau B, Lantieri O, Torchio M, Wiese C, Weber D, Wolswinkel R, Coronel R, Boukens BJ, Bézieau S, Charpentier E, Chatel S, Despres A, Gros F, Kyndt F, Lecointe S, Lindenbaum P, Portero V, Violleau J, Gessler M, Tan HL, Roden DM, Christoffels VM, Le Marec H, Wilde AA, Probst V, Schott JJ, Dina C, Redon R.
Nat Genet. 2013 Jul 21. doi: 10.1038/ng.2712. [Epub ahead of print]

The association of smoking status with healthcare utilisation, productivity loss and resulting costs: results from the population-based KORA F4 study.
Wacker M, Holle R, Heinrich J, Ladwig KH, Peters A, Leidl R, Menn P.
BMC Health Serv Res. 2013 Jul 17;13:278. doi: 10.1186/1472-6963-13-278.

Positron emission tomography based in-vivo imaging of early phase stem cell retention after intramyocardial delivery in the mouse model.
Lang C, Lehner S, Todica A, Boening G, Franz WM
, Bartenstein P, Hacker M, David R.
Eur J Nucl Med Mol Imaging. 2013 Jul 17. [Epub ahead of print]

A genome-wide association study identifies 6p21 as novel risk locus for dilated cardiomyopathy.
Meder B, Rühle F, Weis T, Homuth G, Keller A, Franke J, Peil B, Lorenzo Bermejo J, Frese K, Huge A, Witten A, Vogel B, Haas J, Völker U, Ernst F, Teumer A, Ehlermann P, Zugck C, Friedrichs F, Kroemer H, Dörr M, Hoffmann W, Maisch B, Pankuweit S, Ruppert V, Scheffold T, Kühl U, Schultheiss HP, Kreutz R, Ertl G, Angermann C, Charron P, Villard E, Gary F, Isnard R, Komajda M, Lutz M, Meitinger T, Sinner MF, Wichmann HE, Krawczak M, Ivandic B, Weichenhan D, Gelbrich G, El-Mokhtari NE, Schreiber S, Felix SB, Hasenfuß G, Pfeufer A, Hübner N, Kääb S, Arbustini E, Rottbauer W, Frey N, Stoll M, Katus HA.
Eur Heart J. 2013 Jul 12. [Epub ahead of print]

ELAC2 Mutations Cause a Mitochondrial RNA Processing Defect Associated with Hypertrophic Cardiomyopathy.

Haack TB, Kopajtich R, Freisinger P, Wieland T, Rorbach J, Nicholls TJ, Baruffini E, Walther A, Danhauser K, Zimmermann FA, Husain RA, Schum J, Mundy H, Ferrero I, Strom TM, Meitinger T, Taylor RW, Minczuk M, Mayr JA, Prokisch H.
Am J Hum Genet. 2013 Jul 9. doi:pii: S0002-9297(13)00275-9. 10.1016/j.ajhg.2013.06.006. [Epub ahead of print]

Angiopoietin 2 mediates microvascular and hemodynamic alterations in sepsis.
Ziegler T, Horstkotte J, Schwab C, Pfetsch V, Weinmann K, Dietzel S, Rohwedder I, Hinkel R, Gross L, Lee S, Hu J, Soehnlein O, Franz WM, Sperandio M, Pohl U, Thomas M, Weber C, Augustin HG, Fässler R, Deutsch U, Kupatt C.
J Clin Invest. 2013 Jul 1. doi:pii: 66549. 10.1172/JCI66549. [Epub ahead of print]

[Percutaneous mitral valve repair with the MitraClip® procedure : Patient eligibility criteria.]
Braun D, Orban M, Tittus J, Näbauer M, Hagl C, Massberg S
, Hausleiter J.
Herz. 2013 Jun 26. [Epub ahead of print] German.

Thrombocytosis as a Response to High Interleukin-6 Levels in cGMP-Dependent Protein Kinase I Mutant Mice.
Zhang L, Lukowski R, Gaertner F, Lorenz M, Legate KR, Domes K, Angermeier E, Hofmann F, Massberg S
.
Arterioscler Thromb Vasc Biol. 2013 Jun 20. [Epub ahead of print]

SDF-1 Fused to a Fractalkine Stalk and a Gpi Anchor Enables Functional Neovascularization.
Stachel G, Trenkwalder
T, Götz F, El Aouni C, Muenchmeier N, Pfosser A, Nussbaum C, Sperandio M, Hatzopoulos AK, Hinkel R, Jon Nelson P, Kupatt C.
Stem Cells. 2013 Jun 6. doi: 10.1002/stem.1439. [Epub ahead of print]

Sex-stratified Genome-wide Association Studies Including 270,000 Individuals Show Sexual Dimorphism in Genetic Loci for Anthropometric Traits.
Randall JC, Winkler TW, Kutalik Z, Berndt SI, Jackson AU, Monda KL, Kilpeläinen TO, Esko T, Mägi R, Li S, Workalemahu T, Feitosa MF, Croteau-Chonka DC, Day FR, Fall T, Ferreira T, Gustafsson S, Locke AE, Mathieson I, Scherag A, Vedantam S, Wood AR, Liang L, Steinthorsdottir V, Thorleifsson G, Dermitzakis ET, Dimas AS, Karpe F, Min JL, Nicholson G, Clegg DJ, Person T, Krohn JP, Bauer S, Buechler C, Eisinger K; DIAGRAM Consortium, Bonnefond A, Froguel P; MAGIC Investigators, Hottenga JJ, Prokopenko I, Waite LL, Harris TB, Smith AV, Shuldiner AR, McArdle WL, Caulfield MJ, Munroe PB, Grönberg H, Chen YD, Li G, Beckmann JS, Johnson T, Thorsteinsdottir U, Teder-Laving M, Khaw KT, Wareham NJ, Zhao JH, Amin N, Oostra BA, Kraja AT, Province MA, Cupples LA, Heard-Costa NL, Kaprio J, Ripatti S, Surakka I, Collins FS, Saramies J, Tuomilehto J, Jula A, Salomaa V, Erdmann J, Hengstenberg C, Loley C, Schunkert H
, et al.
PLoS Genet. 2013 Jun;9(6):e1003500. doi: 10.1371/journal.pgen.1003500. Epub 2013 Jun 6.

Genetics of coronary artery disease and myocardial infarction--2013.
Kessler T, Erdmann
J, Schunkert H.
Curr Cardiol Rep. 2013 Jun;15(6):368. doi: 10.1007/s11886-013-0368-0.

Crossroads of coagulation and innate immunity: the case of deep vein thrombosis.
Schulz C, Engelmann B, Massberg S
.
J Thromb Haemost. 2013 Jun;11 Suppl 1:233-41. doi: 10.1111/jth.12261.

The role of adiposity in cardiometabolic traits: a mendelian randomization analysis.
Fall T, Hägg S, Mägi R, Ploner A, Fischer K, Horikoshi M, Sarin AP, Thorleifsson G, Ladenvall C, Kals M, Kuningas M, Draisma HH, Ried JS, van Zuydam NR, Huikari V, Mangino M, Sonestedt E, Benyamin B, Nelson CP, Rivera NV, Kristiansson K, Shen HY, Havulinna AS, Dehghan A, Donnelly LA, Kaakinen M, Nuotio ML, Robertson N, de Bruijn RF, Ikram MA, Amin N, Balmforth AJ, Braund PS, Doney AS, Döring A, Elliott P, Esko T, Franco OH, Gretarsdottir S, Hartikainen AL, Heikkilä K, Herzig KH, Holm H, Hottenga JJ, Hyppönen E, Illig T, Isaacs A, Isomaa B, Karssen LC, Kettunen J, Koenig W, Kuulasmaa K, Laatikainen T, Laitinen J, Lindgren C, Lyssenko V, Läärä E, Rayner NW, Männistö S, Pouta A, Rathmann W, Rivadeneira F, Ruokonen A, Savolainen MJ, Sijbrands EJ, Small KS, Smit JH, Steinthorsdottir V, Syvänen AC, Taanila A, Tobin MD, Uitterlinden AG, Willems SM, Willemsen G, Witteman J, Perola M, Evans A, Ferrières J, Virtamo J, Kee F, Tregouet DA, Arveiler D, Amouyel P, Ferrario MM, Brambilla P, Hall AS, Heath AC, Madden PA, Martin NG, Montgomery GW, Whitfield JB, Jula A, Knekt P, Oostra B, van Duijn CM, Penninx BW, Davey Smith G, Kaprio J, Samani NJ, Gieger C, Peters A, Wichmann HE, Boomsma DI, de Geus EJ, Tuomi T, Power C, Hammond CJ, Spector TD, Lind L, Orho-Melander M, Palmer CN, Morris AD, Groop L, Järvelin MR, Salomaa V, Vartiainen E, Hofman A, Ripatti S, Metspalu A, Thorsteinsdottir U, Stefansson K, Pedersen NL, McCarthy MI, Ingelsson E, Prokopenko I; European Network for Genetic and Genomic Epidemiology (ENGAGE) consortium.
PLoS Med. 2013 Jun;10(6):e1001474. doi: 10.1371/journal.pmed.1001474. Epub 2013 Jun 25.

Letter by halle regarding article, "cardiovascular risk of high- versus moderate-intensity aerobic exercise in coronary heart disease patients".

Halle M.
Circulation. 2013 May 28;127(21):e637. doi: 10.1161/CIRCULATIONAHA.112.150441. No abstract available.

Prosthesis sizing for transcatheter aortic valve implantation - Comparison of three dimensional transesophageal echocardiography with multislice computed tomography.
Husser O, Holzamer A, Resch M, Endemann DH, Nunez J, Bodi V, Schmid C, Riegger GA, Gössmann H, Hamer O, Stroszczynski C, Luchner A, Hilker M, Hengstenberg C
.
Int J Cardiol. 2013 May 17. doi:pii: S0167-5273(13)00849-8. 10.1016/j.ijcard.2013.04.182. [Epub ahead of print]

Early venous manifestation of Ehlers-Danlos syndrome Type IV through a novel mutation in COL3A1.
Wendorff H, Pelisek J, Zimmermann A, Mayer K, Seidel H, Weirich G, Hausser I, Siegel C, Zernecke A, Eckstein HH
.
Cardiovasc Pathol. 2013 May 17. doi:pii: S1054-8807(13)00113-0. 10.1016/j.carpath.2013.04.003. [Epub ahead of print]

Antidiabetic gliptins in combination with G-CSF enhances myocardial function and survival after acute myocardial infarction.
Theiss HD, Gross L, Vallaster M, David R, Brunner S, Brenner C, Nathan P, Assmann G, Mueller-Hoecker J, Vogeser M, Steinbeck G, Franz WM
.
Int J Cardiol. 2013 May 10. doi:pii: S0167-5273(13)00768-7. 10.1016/j.ijcard.2013.04.121. [Epub ahead of print]

The human transcriptome is enriched for miRNA-binding sites located in cooperativity-permitting distance.
Rinck A, Preusse M, Laggerbauer B, Lickert H, Engelhardt S
, Theis FJ.
RNA Biol. 2013 May 9;10(6). [Epub ahead of print]

Exercise in the prevention and rehabilitation of breast cancer
Volaklis KA, Halle M
, Tokmakidis SP.
Wien Klin Wochenschr. 2013 May 8. [Epub ahead of print]

A Correction to the Perspective Titled: “STIMulating Stress Fibers in Endothelial Cells".
Gudermann T, Steinritz D.
Sci Signal. 2013 May 7;6(274):er2. No abstract available.

Functional Interaction of Osteogenic Transcription Factors Runx2 and Vdr in Transcriptional Regulation of Opn during Soft Tissue Calcification.
Sowa AK, Kaiser FJ, Eckhold J, Kessler T, Aherrahrou R, Wrobel S, Kaczmarek PM, Doehring L, Schunkert H
, Erdmann J, Aherrahrou Z.
Am J Pathol. 2013 May 2. doi:pii: S0002-9440(13)00263-0. 10.1016/j.ajpath.2013.03.007. [Epub ahead of print]

Endothelial CSN5 impairs NF-κB activation and monocyte adhesion to endothelial cells and is highly expressed in human atherosclerotic lesions.
Asare Y, Shagdarsuren E, Schmid J, Tilstam PV, Grommes J, El Bounkari O, Schütz AK, Weber C
, de Winther MP, Noels H, Bernhagen J.
Thromb Haemost. 2013 May 2;110(1). [Epub ahead of print]

Individual daytime noise exposure during routine activities and heart rate variability in adults: a repeated measures study.
Kraus U, Schneider A, Breitner S, Hampel R, Rückerl R, Pitz M, Geruschkat U, Belcredi P, Radon K, Peters A.
Environ Health Perspect. 2013 May;121(5):607-12. doi: 10.1289/ehp.1205606. Epub 2013 Mar 18.

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.
Berndt SI, Gustafsson S, Mägi R, Ganna A, Wheeler E, Feitosa MF, Justice AE, Monda KL, Croteau-Chonka DC, Day FR, Esko T, Fall T, Ferreira T, Gentilini D, Jackson AU, Luan J, Randall JC, Vedantam S, Willer CJ, Winkler TW, Wood AR, Workalemahu T, Hu YJ, Lee SH, Liang L, Lin DY, Min JL, Neale BM, Thorleifsson G, Yang J, Albrecht E, Amin N, Bragg-Gresham JL, Cadby G, den Heijer M, Eklund N, Fischer K, Goel A, Hottenga JJ, Huffman JE, Jarick I, Johansson A, Johnson T, Kanoni S, Kleber ME, König IR, Kristiansson K, Kutalik Z, Lamina C, Lecoeur C, Li G, Mangino M, McArdle WL, Medina-Gomez C, Müller-Nurasyid M, et al.
Nat Genet. 2013 Apr 26;45(5):501-12. doi: 10.1038/ng.2606. Epub 2013 Apr 7.

MiR-378 Controls Cardiac Hypertrophy by Combined Repression of MAP Kinase Pathway Factors.
Ganesan J, Ramanujam D, Sassi Y, Ahles A, Jentzsch C, Werfel S, Leierseder S, Loyer X, Giacca M, Zentilin L, Thum T, Laggerbauer B, Engelhardt S
.
Circulation. 2013 Apr 26. [Epub ahead of print]

MicroRNAs in flow-dependent vascular remodeling.
Neth P, Nazari-Jahantigh M, Schober A, Weber C
.
Cardiovasc Res. 2013 Apr 23. [Epub ahead of print]

Three-dimensional transoesophageal echocardiography for the assessment of clip attachment to the leaflets in percutaneous edge-to-edge repair of the mitral valve.
Braun D, Orban M, Michalk F, Barthel P, Hoppe K, Sonne C, Lesevic H, Pache J, Mehilli J, Kastrati A, Hausleiter J, Massberg S.
EuroIntervention. 2013 Apr 22;8(12):1379-87. doi: 10.4244/EIJV8I12A211.

Early Vessel Destabilization Mediated by Angiopoietin-2 and Subsequent Vessel Maturation via Angiopoietin-1 Induce Functional Neovasculature after Ischemia.
Qin D, Trenkwalder T, Lee S, Chillo O, Deindl E, Kupatt C
, Hinkel R.
PLoS One. 2013 Apr 16;8(4):e61831. doi: 10.1371/journal.pone.0061831. Print 2013.

Effects of smoking on arterial distensibility, central aortic pressures and left ventricular mass.
Markus MR, Stritzke J, Baumeister SE, Siewert U, Baulmann J, Hannemann A, Schipf S, Meisinger C, Dörr M, Felix SB, Keil U, Völzke H, Hense HW, Schunkert H
; The MONICA/KORA Augsburg Cohort Study.
Int J Cardiol. 2013 Apr 15. doi:pii: S0167-5273(13)00464-6. 10.1016/j.ijcard.2013.03.045. [Epub ahead of print]

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.
den Hoed M, Eijgelsheim M, Esko T, Brundel BJ, Peal DS, Evans DM, Nolte IM, Segrè AV, Holm H, Handsaker RE, Westra HJ, Johnson T, Isaacs A, Yang J, Lundby A, Zhao JH, Kim YJ, Go MJ, Almgren P, Bochud M, Boucher G, Cornelis MC, Gudbjartsson D, Hadley D, van der Harst P, Hayward C, den Heijer M, Igl W, Jackson AU, Kutalik Z, Luan J, Kemp JP, Kristiansson K, Ladenvall C, Lorentzon M, Montasser ME, Njajou OT, O'Reilly PF, Padmanabhan S, St Pourcain B, Rankinen T, Salo P, Tanaka T, Timpson NJ, Vitart V, Waite L, Wheeler W, Zhang W, Draisma HH, Feitosa MF, Kerr KF, Lind PA, Mihailov E, et al.
Nat Genet. 2013 Apr 14. doi: 10.1038/ng.2610. [Epub ahead of print]

Negating the dominant-negative allele: a new treatment paradigm for arrhythmias explored in human induced pluripotent stem cell-derived cardiomyocytes.
Sinnecker D, Moretti A, Laugwitz KL
.
Eur Heart J. 2013 Apr 12. [Epub ahead of print] No abstract available.

Gap junctional communication promotes apoptosis in a connexin-type-dependent manner.
Kameritsch P, Khandoga N, Pohl U
, Pogoda K.
Cell Death Dis. 2013 Apr 11;4:e584. doi: 10.1038/cddis.2013.105.

The role of co-morbidity in the selection of antidiabetic pharmacotherapy in type-2 diabetes.
Tschöpe D, Hanefeld M, Meier JJ, Gitt AK, Halle M, Bramlage P, Schumm-Draeger PM.
Cardiovasc Diabetol. 2013 Apr 10;12(1):62. [Epub ahead of print]

Identification of seven loci affecting mean telomere length and their association with disease.
Codd V, Nelson CP, Albrecht E, Mangino M, Deelen J, Buxton JL, Hottenga JJ, Fischer K, Esko T, Surakka I, Broer L, Nyholt DR, Mateo Leach I, Salo P, Hägg S, Matthews MK, Palmen J, Norata GD, O'Reilly PF, Saleheen D, Amin N, Balmforth AJ, Beekman M, de Boer RA, Böhringer S, Braund PS, Burton PR, de Craen AJ, Denniff M, Dong Y, Douroudis K, Dubinina E, Eriksson JG, Garlaschelli K, Guo D, Hartikainen AL, Henders AK, Houwing-Duistermaat JJ, Kananen L, Karssen LC, Kettunen J, Klopp N, Lagou V, van Leeuwen EM, Madden PA, Mägi R, Magnusson PK, Männistö S, McCarthy MI, Medland SE, Mihailov E, Montgomery GW, Oostra BA, Palotie A, Peters A, Pollard H, Pouta A, Prokopenko I, Ripatti S, Salomaa V, Suchiman HE, Valdes AM, Verweij N, Viñuela A, Wang X, Wichmann HE, Widen E, Willemsen G, Wright MJ, Xia K, Xiao X, van Veldhuisen DJ, Catapano AL, Tobin MD, Hall AS, Blakemore AI, van Gilst WH, Zhu H, Consortium C, Erdmann J, Reilly MP, Kathiresan S, Schunkert H, Talmud PJ, Pedersen NL, Perola M, Ouwehand W, Kaprio J, Martin NG, van Duijn CM, Hovatta I, Gieger C, Metspalu A, Boomsma DI, Jarvelin MR, Slagboom PE, Thompson JR, Spector TD, van der Harst P, Samani NJ.
Nat Genet. 2013 Apr;45(4):422-7, 427e1-2. doi: 10.1038/ng.2528.

Clinical utility gene card for: Long-QT syndrome (types 1-13).

Beckmann BM, Wilde AA, Kääb S.
Eur J Hum Genet. 2013 Mar 20. doi: 10.1038/ejhg.2013.28. [Epub ahead of print] No abstract available.

The microRNA-342-5p Fosters Inflammatory Macrophage Activation Through an Akt1- and microRNA-155-Dependent Pathway during Atherosclerosis.
Wei Y, Nazari-Jahantigh M, Chan L, Zhu M, Heyll K, Corbalán-Campos J, Hartmann P, Thiemann A, Weber C, Schober A.
Circulation. 2013 Mar 19. [Epub ahead of print]

STIMulating Stress Fibers in Endothelial Cells.
Gudermann T, Steinritz D.
Sci Signal. 2013 Mar 19;6(267):pe8. doi: 10.1126/scisignal.2004051.

Simple Risk Model Predicts Incidence of Atrial Fibrillation in a Racially and Geographically Diverse Population: the CHARGE-AF Consortium.
Alonso A, Krijthe BP, Aspelund T, Stepas KA, Pencina MJ, Moser CB, Sinner MF, Sotoodehnia N, Fontes JD, Janssens AC, Kronmal RA, Magnani JW, Witteman JC, Chamberlain AM, Lubitz SA, Schnabel RB, Agarwal SK, McManus DD, Ellinor PT, Larson MG, Burke GL, Launer LJ, Hofman A, Levy D, Gottdiener JS, Kääb S, Couper D, Harris TB, Soliman EZ, Stricker BH, Gudnason V, Heckbert SR, Benjamin EJ.
J Am Heart Assoc. 2013 Mar 18;2(2):e000102. doi: 10.1161/JAHA.112.000102.

Genetic Predisposition to Higher Blood Pressure Increases Coronary Artery Disease Risk.
Lieb W, Jansen H, Loley C, Pencina MJ, Nelson CP, Newton-Cheh C, Kathiresan S, Reilly MP, Assimes TL, Boerwinkle E, Hall AS, Hengstenberg C, Laaksonen R, McPherson R, Thorsteinsdottir U, Ziegler A, Peters A, Thompson JR, König IR, Erdmann J, Samani NJ, Vasan RS, Schunkert H; on behalf of CARDIoGRAM.
*Hypertension. 2013 Mar 11. [Epub ahead of print]

Go with the flow: The passion for vascular biology research. Highlights from IVBM 2012.
Preissner KT, Weber C.
Thromb Haemost. 2013 Mar 5;109(3):366-7. doi: 10.1160/TH13-02-0105. Epub 2013 Feb 14. No abstract available.

Calmodulin mutations associated with recurrent cardiac arrest in infants.
Crotti L, Johnson CN, Graf E, De Ferrari GM, Cuneo BF, Ovadia M, Papagiannis J, Feldkamp MD, Rathi SG, Kunic JD, Pedrazzini M, Wieland T, Lichtner P, Beckmann BM, Clark T, Shaffer C, Benson DW, Kääb S, Meitinger T, Strom TM, Chazin WJ, Schwartz PJ, George AL Jr.
Circulation. 2013 Mar 5;127(9):1009-17. doi: 10.1161/CIRCULATIONAHA.112.001216. Epub 2013 Feb 6.

MicroRNA29: A Mechanistic Contributor and Potential Biomarker in Atrial Fibrillation.

Dawson K, Wakili R, Ordög B, Clauss S, Chen Y, Iwasaki Y, Voigt N, Qi XY, Sinner MF, Dobrev D, Kääb S, Nattel S.
Circulation. 2013 Mar 4. [Epub ahead of print]

Neutrophil-derived cathelicidin promotes adhesion of classical monocytes.

Wantha S, Alard JE, Megens RT, van der Does AM, Döring Y, Drechsler M, Pham CT, Wang MW, Wang JM, Gallo RL, von Hundelshausen P, Lindbom L, Hackeng T, Weber C, Soehnlein O.
Circ Res. 2013 Mar 1;112(5):792-801. doi: 10.1161/CIRCRESAHA.112.300666. Epub 2013 Jan 2.

MicroRNA-126, -145, and -155: A Therapeutic Triad in Atherosclerosis?

Wei Y, Nazari-Jahantigh M, Neth P, Weber C, Schober A.
Arterioscler Thromb Vasc Biol. 2013 Mar;33(3):449-54. doi: 10.1161/ATVBAHA.112.300279. Epub 2013 Jan 16.

Free breathing real-time cardiac cine imaging with improved spatial resolution at 3 T.

Schwab F, Schwarz F, Dietrich O, Lanz T, Resmer F, Wichmann T, Wintersperger BJ, Bamberg F, Nikolaou K, Reiser M, Theisen D.
Invest Radiol. 2013 Mar;48(3):158-66. doi: 10.1097/RLI.0b013e31827f1b68.

Nitric Oxide-Donating Statins Upgrade the Benefits of Lipid-Lowering in Vascular Inflammation by Desensitizing Neutrophil Activation : Editorial to: "Nitric Oxide-donating atorvastatin attenuates neutrophil recruitment during vascular inflammation independent of changes in plasma cholesterol" by R. Baetta et al.

Drechsler M, Soehnlein O, Weber C.
Cardiovasc Drugs Ther. 2013 Feb 26. [Epub ahead of print] No abstract available.

The Cardio-Metabolic Risk of Moderate and Severe Obesity in Children and Adolescents.
Rank M, Siegrist M, Wilks DC, Langhof H, Wolfarth B, Haller B, Koenig W, Halle M.
J Pediatr. 2013 Feb 20. doi:pii: S0022-3476(13)00044-9. 10.1016/j.jpeds.2013.01.020. [Epub ahead of print]

Distinct functions of chemokine receptor axes in the atherogenic mobilization and recruitment of classical monocytes.

Soehnlein O, Drechsler M, Döring Y, Lievens D, Hartwig H, Kemmerich K, Ortega-Gómez A, Mandl M, Vijayan S, Projahn D, Garlichs CD, Koenen RR, Hristov M, Lutgens E, Zernecke A, Weber C.
EMBO Mol Med. 2013 Feb 18. doi: 10.1002/emmm.201201717. [Epub ahead of print]

Somatic mutations in ATP1A1 and ATP2B3 lead to aldosterone-producing adenomas and secondary hypertension.

Beuschlein F, Boulkroun S, Osswald A, Wieland T, Nielsen HN, Lichtenauer UD, Penton D, Schack VR, Amar L, Fischer E, Walther A, Tauber P, Schwarzmayr T, Diener S, Graf E, Allolio B, Samson-Couterie B, Benecke A, Quinkler M, Fallo F, Plouin PF, Mantero F, Meitinger T, Mulatero P, Jeunemaitre X, Warth R, Vilsen B, Zennaro MC, Strom TM, Reincke M.
Nat Genet. 2013 Feb 17. doi: 10.1038/ng.2550. [Epub ahead of print]

Leptin, adiponectin, and short-term and long-term weight loss after a lifestyle intervention in obese children.

Siegrist M, Rank M, Wolfarth B, Langhof H, Haller B, Koenig W, Halle M.
Nutrition. 2013 Feb 16. doi:pii: S0899-9007(12)00478-9. 10.1016/j.nut.2012.12.011. [Epub ahead of print]

Pathogenic arterial remodeling: the good and bad in microRNAs.

Wei Y, Schober A, Weber C.
Am J Physiol Heart Circ Physiol. 2013 Feb 8. [Epub ahead of print]

CXCL12 Promotes the Stabilization of Atherosclerotic Lesions Mediated by Smooth Muscle Progenitor Cells in Apoe-Deficient Mice.

Akhtar S, Gremse F, Kiessling F, Weber C, Schober A.
Arterioscler Thromb Vasc Biol. 2013 Feb 7. [Epub ahead of print]

MicroRNAs: from basic mechanisms to clinical application in cardiovascular medicine.

Weber C.
Arterioscler Thromb Vasc Biol. 2013 Feb;33(2):168-9. doi: 10.1161/ATVBAHA.112.300920. No abstract available.

High-resolution cine MRI with TGRAPPA for fast assessment of left ventricular function at 3Tesla.

Theisen D, Sandner TA, Bamberg F, Bauner KU, Schwab F, Schwarz F, Arnoldi E, Reiser MF, Wintersperger BJ.
Eur J Radiol. 2013 Jan 23. doi:pii: S0720-048X(13)00004-1. 10.1016/j.ejrad.2012.12.019. [Epub ahead of print]

Novel single-source high-pitch protocol for CT angiography of the aorta: comparison to high-pitch dual-source protocol in the context of TAVI planning.

Bischoff B, Meinel FG, Reiser M, Becker HC.
Int J Cardiovasc Imaging. 2013 Jan 19. [Epub ahead of print]

Directing Cardiomyogenic Differentiation of Human Pluripotent Stem Cells by Plasmid-Based Transient Overexpression of Cardiac Transcription Factors.

Hartung S, Schwanke K, Haase A, David R, Franz WM, Martin U, Zweigerdt R.
Stem Cells Dev. 2013 Jan 18. [Epub ahead of print]

Impact of common regulatory single-nucleotide variants on gene expression profiles in whole blood.

Mehta D, Heim K, Herder C, Carstensen M, Eckstein G, Schurmann C, Homuth G, Nauck M, Völker U, Roden M, Illig T, Gieger C, Meitinger T, Prokisch H.
Eur J Hum Genet. 2013 Jan;21(1):48-54. doi: 10.1038/ejhg.2012.106. Epub 2012 Jun 13.

Large-scale association analysis identifies new risk loci for coronary artery disease.

CARDIoGRAMplusC4D Consortium, Deloukas P, Kanoni S, Willenborg C, Farrall M, Assimes TL, Thompson JR, Ingelsson E, Saleheen D, Erdmann J, Goldstein BA, Stirrups K, König IR, Cazier JB, Johansson A, Hall AS, Lee JY, Willer CJ, Chambers JC, Esko T, Folkersen L, Goel A, Grundberg E, Havulinna AS, Ho WK, Hopewell JC, Eriksson N, Kleber ME, Kristiansson K, Lundmark P, Lyytikäinen LP, Rafelt S, Shungin D, Strawbridge RJ, Thorleifsson G, Tikkanen E, Van Zuydam N, Voight BF, Waite LL, Zhang W, Ziegler A, Absher D, Altshuler D, Balmforth AJ, Barroso I, Braund PS, Burgdorf C, Claudi-Boehm S, Cox D, Dimitriou M, Do R; DIAGRAM Consortium; CARDIOGENICS Consortium, Doney AS, El Mokhtari N, Eriksson P, Fischer K, Fontanillas P, Franco-Cereceda A, Gigante B, Groop L, Gustafsson S, Hager J, Hallmans G, Han BG, Hunt SE, Kang HM, Illig T, Kessler T, Knowles JW, Kolovou G, Kuusisto J, Langenberg C, Langford C, Leander K, Lokki ML, Lundmark A, McCarthy MI, Meisinger C, Melander O, Mihailov E, Maouche S, Morris AD, Müller-Nurasyid M; MuTHER Consortium, Nikus K, Peden JF, Rayner NW, Rasheed A, Rosinger S, Rubin D, Rumpf MP, Schäfer A, Sivananthan M, Song C, Stewart AF, Tan ST, Thorgeirsson G, van der Schoot CE, Wagner PJ; Wellcome Trust Case Control Consortium, Wells GA, Wild PS, Yang TP, Amouyel P, Arveiler D, Basart H, Boehnke M, Boerwinkle E, Brambilla P, Cambien F, Cupples AL, de Faire U, Dehghan A, Diemert P, Epstein SE, Evans A, Ferrario MM, Ferrières J, Gauguier D, Go AS, Goodall AH, Gudnason V, Hazen SL, Holm H, Iribarren C, Jang Y, Kähönen M, Kee F, Kim HS, Klopp N, Koenig W, Kratzer W, Kuulasmaa K, Laakso M, Laaksonen R, Lee JY, Lind L, Ouwehand WH, Parish S, Park JE, Pedersen NL, Peters A, Quertermous T, Rader DJ, Salomaa V, Schadt E, Shah SH, Sinisalo J, Stark K, Stefansson K, Trégouët DA, Virtamo J, Wallentin L, Wareham N, Zimmermann ME, Nieminen MS, Hengstenberg C, Sandhu MS, Pastinen T, Syvänen AC, Hovingh GK, Dedoussis G, Franks PW, Lehtimäki T, Metspalu A, Zalloua PA, Siegbahn A, Schreiber S, Ripatti S, Blankenberg SS, Perola M, Clarke R, Boehm BO, O'Donnell C, Reilly MP, März W, Collins R, Kathiresan S, Hamsten A, Kooner JS, Thorsteinsdottir U, Danesh J, Palmer CN, Roberts R, Watkins H, Schunkert H, Samani NJ.
Nat Genet. 2013 Jan;45(1):25-33. doi: 10.1038/ng.2480. Epub 2012 Dec 2.

Selection of a common multipotent cardiovascular stem cell using the 3.4-kb MesP1 promoter fragment.

David R, Schwarz F, Rimmbach C, Nathan P, Jung J, Brenner C, Jarsch V, Stieber J, Franz WM.
Basic Res Cardiol. 2013 Jan;108(1):312. doi: 10.1007/s00395-012-0312-2. Epub 2012 Nov 18.

Capillary and arteriolar pericytes attract innate leukocytes exiting through venules and 'instruct' them with pattern-recognition and motility programs.

Stark K, Eckart A, Haidari S, Tirniceriu A, Lorenz M, von Brühl ML, Gärtner F, Khandoga AG, Legate KR, Pless R, Hepper I, Lauber K, Walzog B, Massberg S.
Nat Immunol. 2013 Jan;14(1):41-51. doi: 10.1038/ni.2477. Epub 2012 Nov 25.

[Magnetic resonance imaging of hypertrophic cardiomyopathy : evaluation of diastolic function].

Schwarz F, Schwab F, Beckmann BM, Schuessler F, Zinsser D, Gölz T, Kääb S, Reiser MF, Theisen D.
Radiologe. 2013 Jan;53(1):15-23. doi: 10.1007/s00117-012-2381-5. German.

[Magnetic resonance imaging of dilated cardiomyopathy].

D'Anastasi M, Greif M, Reiser MF, Theisen D.
Radiologe. 2013 Jan;53(1):24-9. doi: 10.1007/s00117-012-2382-4. German.

Incremental prognostic value of cardiac CT angiography in patients with acute chest pain.
Schlett CL, Nance JW Jr, Schoepf UJ, Bamberg F.
Radiology. 2013 Jan;266(1):364. No abstract available.

Thrombosis as an intravascular effector of innate immunity.

Engelmann B, Massberg S.
Nat Rev Immunol. 2013 Jan;13(1):34-45. doi: 10.1038/nri3345. Epub 2012 Dec 7. Review.

COMT-Val158Met-Polymorphism Is Not a Risk Factor for Acute Kidney Injury after Cardiac Surgery.
Kornek M, Deutsch MA, Eichhorn S, Lahm H, Wagenpfeil S, Krane M, Lange R, Boehm J.
Dis Markers. 2013;35(2):129-34. doi: 10.1155/2013/279046. Epub 2013 Aug 7.

Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations.

Demirkan A, van Duijn CM, Ugocsai P, Isaacs A, Pramstaller PP, Liebisch G, Wilson JF, Johansson Å, Rudan I, Aulchenko YS, Kirichenko AV, Janssens AC, Jansen RC, Gnewuch C, Domingues FS, Pattaro C, Wild SH, Jonasson I, Polasek O, Zorkoltseva IV, Hofman A, Karssen LC, Struchalin M, Floyd J, Igl W, Biloglav Z, Broer L, Pfeufer A, Pichler I, Campbell S, Zaboli G, Kolcic I, Rivadeneira F, Huffman J, Hastie ND, Uitterlinden A, Franke L, Franklin CS, Vitart V; DIAGRAM Consortium, Nelson CP, Preuss M; CARDIoGRAM Consortium, Bis JC, O'Donnell CJ, Franceschini N; CHARGE Consortium, Witteman JC, Axenovich T, Oostra BA, Meitinger T, Hicks AA, Hayward C, Wright AF, Gyllensten U, Campbell H, Schmitz G; EUROSPAN consortium.
PLoS Genet. 2012;8(2):e1002490. doi: 10.1371/journal.pgen.1002490. Epub 2012 Feb 16.

Visualization of endothelial actin cytoskeleton in the mouse retina.

Fraccaroli A, Franco CA, Rognoni E, Neto F, Rehberg M, Aszodi A, Wedlich-Söldner R, Pohl U, Gerhardt H, Montanez E.
PLoS One. 2012;7(10):e47488.

Fractalkine is expressed in early and advanced atherosclerotic lesions and supports monocyte recruitment via CX3CR1.

Stolla M, Pelisek J, von Brühl ML, Schäfer A, Barocke V, Heider P, Lorenz M, Tirniceriu A, Steinhart A, Bauersachs J, Bray PF, Massberg S, Schulz C.
PLoS One. 2012;7(8):e43572.

Analyzing illumina gene expression microarray data from different tissues: methodological aspects of data analysis in the metaxpress consortium.
Schurmann C, Heim K, Schillert A, Blankenberg S, Carstensen M, Dörr M, Endlich K, Felix SB, Gieger C, Grallert H, Herder C, Hoffmann W, Homuth G, Illig T, Kruppa J, Meitinger T, Müller C, Nauck M, Peters A, Rettig R, Roden M, Strauch K, Völker U, Völzke H, Wahl S, Wallaschofski H, Wild PS, Zeller T, Teumer A, Prokisch H, Ziegler A.
PLoS One. 2012;7(12):e50938.

Should antidiabetic treatment of type 2 diabetes in patients with heart failure differ from that in patients without?
Gitt AK, Halle M, Hanefeld M, Kellerer M, Marx N, Meier JJ, Schumm-Draeger PM, Bramlage P, Tschöpe D.
Eur J Heart Fail. 2012 Dec;14(12):1389-400.

Hydrogen sulfide-releasing aspirin derivative ACS14 exerts strong antithrombotic effects in vitro and in vivo.

Pircher J, Fochler F, Czermak T, Mannell H, Kraemer BF, Wörnle M, Sparatore A, Del Soldato P, Pohl U, Krötz F.
Arterioscler Thromb Vasc Biol. 2012 Dec;32(12):2884-91.

Validity of cardiac implantable electronic devices in assessing daily physical activity.

Pressler A, Danner M, Esefeld K, Haller B, Scherr J, Schömig A, Halle M, Kolb C.
Int J Cardiol. 2012 Nov 29. doi:pii: S0167-5273(12)01533-1. 10.1016/j.ijcard.2012.11.050. [Epub ahead of print]

Motor training of sixty minutes once per week improves motor ability in children with congenital heart disease and retarded motor development: a pilot study.

Müller J, Pringsheim M, Engelhardt A, Meixner J, Halle M, Oberhoffer R, Hess J, Hager A.
Cardiol Young. 2012 Nov 21:1-5. [Epub ahead of print]

Not all beta-blockers are equal in the management of long QT syndrome types 1 and 2: higher recurrence of events under metoprolol.
Chockalingam P, Crotti L, Girardengo G, Johnson JN, Harris KM, van der Heijden JF, Hauer RN, Beckmann BM, Spazzolini C, Rordorf R, Rydberg A, Clur SA, Fischer M, van den Heuvel F, Kääb S, Blom NA, Ackerman MJ, Schwartz PJ, Wilde AA.
J Am Coll Cardiol. 2012 Nov 13;60(20):2092-9. doi: 10.1016/j.jacc.2012.07.046. Epub 2012 Oct 17.

A novel role of sphingosine 1-phosphate receptor S1pr1 in mouse thrombopoiesis.

Zhang L, Orban M, Lorenz M, Barocke V, Braun D, Urtz N, Schulz C, von Brühl ML, Tirniceriu A, Gaertner F, Proia RL, Graf T, Bolz SS, Montanez E, Prinz M, Müller A, von Baumgarten L, Billich A, Sixt M, Fässler R, von Andrian UH, Junt T, Massberg S.
J Exp Med. 2012 Nov 12. [Epub ahead of print]

Acute and chronic effects of exercise on circulating endothelial progenitor cells in healthy and diseased patients.
Volaklis KA, Tokmakidis SP, Halle M.
Clin Res Cardiol. 2012 Nov 2. [Epub ahead of print]

Women and men with stable coronary artery disease have similar clinical outcomes: insights from the international prospective CLARIFY registry.
Steg PG, Greenlaw N, Tardif JC, Tendera M, Ford I, Kääb S, Abergel H, Fox KM, Ferrari R; CLARIFY Registry Investigators.
Eur Heart J. 2012 Nov;33(22):2831-40.

Inhibition of endothelial nitric oxyde synthase increases capillary formation via Rac1-dependent induction of hypoxia-inducible factor-1α and plasminogen activator inhibitor-1.

Petry A, BelAiba RS, Weitnauer M, Görlach A.
Thromb Haemost. 2012 Nov;108(5):849-62.

Improving the treatment of atherosclerosis by linking anti-inflammatory and lipid modulating strategies.
Zernecke A, Weber C.
Heart. 2012 Nov;98(21):1600-6. doi: 10.1136/heartjnl-2012-301761.

An inpatient lifestyle-change programme improves heart rate recovery in overweight and obese children and adolescents (LOGIC Trial).
Wilks DC, Rank M, Christle J, Langhof H, Siegrist M, Halle M.
Eur J Prev Cardiol. 2012 Oct 29. [Epub ahead of print]

FTO genotype is associated with phenotypic variability of body mass index.
Yang J, Loos RJ, Powell JE, Medland SE, Speliotes EK, Chasman DI, Rose LM, Thorleifsson G, Steinthorsdottir V, Mägi R, Waite L, Smith AV, Yerges-Armstrong LM, Monda KL, Hadley D, Mahajan A, Li G, Kapur K, Vitart V, Huffman JE, Wang SR, Palmer C, Esko T, Fischer K, Zhao JH, Demirkan A, Isaacs A, Feitosa MF, Luan J, Heard-Costa NL, White C, Jackson AU, Preuss M, Ziegler A, Eriksson J, Kutalik Z, Frau F, Nolte IM, Van Vliet-Ostaptchouk JV, Hottenga JJ, Jacobs KB, Verweij N, Goel A, Medina-Gomez C, Estrada K, Bragg-Gresham JL, Sanna S, Sidore C, Tyrer J, Teumer A, Prokopenko I, Mangino M, Lindgren CM, Assimes TL, Shuldiner AR, Hui J, Beilby JP, McArdle WL, Hall P, Haritunians T, Zgaga L, Kolcic I, Polasek O, Zemunik T, Oostra BA, Junttila MJ, Grönberg H, Schreiber S, Peters A, Hicks AA, Stephens J, Foad NS, Laitinen J, Pouta A, Kaakinen M, Willemsen G, Vink JM, Wild SH, Navis G, Asselbergs FW, Homuth G, John U, Iribarren C, Harris T, Launer L, Gudnason V, O'Connell JR, Boerwinkle E, Cadby G, Palmer LJ, James AL, Musk AW, Ingelsson E, Psaty BM, Beckmann JS, Waeber G, Vollenweider P, Hayward C, Wright AF, Rudan I, Groop LC, Metspalu A, Khaw KT, van Duijn CM, Borecki IB, Province MA, Wareham NJ, Tardif JC, Huikuri HV, Cupples LA, Atwood LD, Fox CS, Boehnke M, Collins FS, Mohlke KL, Erdmann J, Schunkert H, Hengstenberg C, Stark K, Lorentzon M, Ohlsson C, Cusi D, Staessen JA, Van der Klauw MM, Pramstaller PP, Kathiresan S, Jolley JD, Ripatti S, Jarvelin MR, de Geus EJ, Boomsma DI, Penninx B, Wilson JF, Campbell H, Chanock SJ, van der Harst P, Hamsten A, Watkins H, Hofman A, Witteman JC, Zillikens MC, Uitterlinden AG, Rivadeneira F, Zillikens MC, Kiemeney LA, Vermeulen SH, Abecasis GR, Schlessinger D, Schipf S, Stumvoll M, Tönjes A, Spector TD, North KE, Lettre G, McCarthy MI, Berndt SI, Heath AC, Madden PA, Nyholt DR, Montgomery GW, Martin NG, McKnight B, Strachan DP, Hill WG, Snieder H, Ridker PM, Thorsteinsdottir U, Stefansson K, Frayling TM, Hirschhorn JN, Goddard ME, Visscher PM.
Nature. 2012 Oct 11;490(7419):267-72. doi: 10.1038/nature11401. Epub 2012 Sep 16.

Molecular and cellular mechanisms of thymosin β4-mediated cardioprotection.
Hinkel R, Trenkwalder T, Kupatt C.
Ann N Y Acad Sci. 2012 Oct;1269(1):102-109. doi: 10.1111/j.1749-6632.2012.06693.x.

MicroRNA-155 promotes atherosclerosis by repressing Bcl6 in macrophages.
Nazari-Jahantigh M, Wei Y, Noels H, Akhtar S, Zhou Z, Koenen RR, Heyll K, Gremse F, Kiessling F, Grommes J, Weber C, Schober A.
J Clin Invest. 2012 Oct 8. pii: 61716. doi: 10.1172/JCI61716. [Epub ahead of print]

Visualization of vascular inflammation in the atherosclerotic mouse by ultrasmall superparamagnetic iron oxide vascular cell adhesion molecule-1-specific nanoparticles.
Michalska M, Machtoub L, Manthey HD, Bauer E, Herold V, Krohne G, Lykowsky G, Hildenbrand M, Kampf T, Jakob P, Zernecke A, Bauer WR.
Arterioscler Thromb Vasc Biol. 2012 Oct;32(10):2350-7. Epub 2012 Aug 9.

Myocardial regeneration by transplantation of modified endothelial progenitor cells expressing SDF-1 in a rat model.
Schuh A, Kroh A, Konschalla S, Liehn EA, Sobota RM, Biessen EA, Bot I, Tolga Taha S, Schober A, Marx N, Weber C, Sasse A.
J Cell Mol Med. 2012 Oct;16(10):2311-20. doi: 10.1111/j.1582-4934.2012.01539.x.

The miRNA-212/132 family regulates both cardiac hypertrophy and cardiomyocyte autophagy.

Ucar A, Gupta SK, Fiedler J, Erikci E, Kardasinski M, Batkai S, Dangwal S, Kumarswamy R, Bang C, Holzmann A, Remke J, Caprio M, Jentzsch C, Engelhardt S, Geisendorf S, Glas C, Hofmann TG, Nessling M, Richter K, Schiffer M, Carrier L, Napp LC, Bauersachs J, Chowdhury K, Thum T.
Nat Commun. 2012 Sep 25;3:1078. doi: 10.1038/ncomms2090.

Interval versus continuous training in lung transplant candidates: A randomized trial.
Gloeckl R, Halle M, Kenn K.
J Heart Lung Transplant. 2012 Sep;31(9):934-41.

Fractalkine Is Expressed in Early and Advanced Atherosclerotic Lesions and Supports Monocyte Recruitment via CX3CR1.
Stolla M, Pelisek J, von Brühl ML, Schäfer A, Barocke V, Heider P, Lorenz M, Tirniceriu A, Steinhart A, Bauersachs J, Bray PF, Massberg S, Schulz C.
PLoS One. 2012;7(8):e43572. Epub 2012 Aug 20.

Heart Transplantation in a 36-Year-Old Experiencing Terminal Heart Failure Caused by Systemic Sclerosis.
Martens E, Lange P, Pohl T, Nickel T, Juchem G, Kaczmarek I, Theisen D, Sotlar K, Steinbeck G, Kääb S, Theiss HD.
Transplantation. 2012 Jul 27;94(2):e13-e15. No abstract available.

Role of microparticles as messengers enhancing stem cell activity after genetic engineering.
Liehn EA, Bucur O, Weber C.
Circ Res. 2012 Jul 20;111(3):265-7. No abstract available.

Left ventricular thrombus formation after successful percutaneous edge-to-edge mitral valve repair.
Orban M, Lesevic H, Massberg S, Hausleiter J.
Eur Heart J. 2012 Aug 16. [Epub ahead of print]

Do we know enough about the immune pathogenesis of acute coronary syndromes to improve clinical practice?
Matusik P, Guzik B, Weber C, Guzik TJ.
Thromb Haemost. 2012 Aug 7;108(3).

Small RNA biomarkers come of age.
Engelhardt S.
J Am Coll Cardiol. 2012 Jul 24;60(4):300-3.

Detection of Anti β1-AR Auto-Antibodies in Heart Failure by a Cell-Based Competition ELISA.
Holthoff HP, Zeibig S, Boivin V, Bauer J, Lohse MJ, Kääb S, Clauss S, Jahns R, Schlipp A, Münch G, Ungerer M.
Circ Res. 2012 Jul 18. [Epub ahead of print]

Touch of Chemokines.
Blanchet X, Langer M, Weber C, Koenen RR, von Hundelshausen P.
Front Immunol. 2012;3:175. Epub 2012 Jul 12.

A meta-analysis of genome-wide association studies of the electrocardiographic early repolarization pattern.
Sinner MF, Porthan K, Noseworthy PA, Havulinna AS, Tikkanen J, Müller-Nurasyid M, Peloso G, Ulivi S, Beckmann BM, Brockhaus AC, Cooper RR, Gasparini P, Hengstenberg C, Hwang SJ, Iorio A, Junttila MJ, Klopp N, Kähönen M, Laaksonen MA, Lehtimäki T, Lichtner P, Lyytikäinen LP, Martens E, Meisinger C, Meitinger T, Merchant FM, Nieminen MS, Peters A, Pietilä A, Perz S, Oikarinen L, Raitakari O, Reinhard W, Silander K, Thorand B, Wichmann HE, Sinagra G, Viikari J, O'Donnell CJ, Ellinor PT, Huikuri HV, Kääb S, Newton-Cheh C, Salomaa V.
Heart Rhythm. 2012 Jun 6. [Epub ahead of print]

Associations between Borg's rating of perceived exertion and physiological measures of exercise intensity.
Scherr J, Wolfarth B, Christle JW, Pressler A, Wagenpfeil S, Halle M.
Eur J Appl Physiol. 2012 May 22. [Epub ahead of print]

Role of cold shock Y-box protein-1 in inflammation, atherosclerosis and organ transplant rejection.
Raffetseder U, Liehn EA, Weber C, Mertens PR.
Eur J Cell Biol. 2012 Jun;91(6-7):567-75.

Hematopoietic Interferon Regulatory Factor 8-Deficiency Accelerates Atherosclerosis in Mice.
Döring Y, Soehnlein O, Drechsler M, Shagdarsuren E, Chaudhari S, Meiler S, Hartwig H, Hristov M, Koenen RR, Hieronymus T, Zenke M, Weber C, Zernecke A.
Arterioscler Thromb Vasc Biol. 2012 May 3. [Epub ahead of print]

Adjuvant early and late cardioprotective therapy: access to the heart.
Hinkel R, Boekstegers P, Kupatt C.
Cardiovasc Res. 2012 May 1;94(2):226-36.

Contribution of Platelet CX3CR1 to Platelet-Monocyte Complex Formation and Vascular Recruitment During Hyperlipidemia.
Postea O, Vasina EM, Cauwenberghs S, Projahn D, Liehn EA, Lievens D, Theelen W, Kramp BK, Dragomir Butoi E, Soehnlein O, Heemskerk JW, Ludwig A, Weber C, Koenen RR.
Arterioscler Thromb Vasc Biol. 2012 May;32(5):1186-93.

Disruption of platelet-derived chemokine heteromers prevents neutrophil extravasation in acute lung injury.
Grommes J, Alard JE, Drechsler M, Wantha S, Mörgelin M, Kuebler WM, Jacobs M, von Hundelshausen P, Markart P, Wygrecka M, Preissner KT, Hackeng TM, Koenen RR, Weber C, Soehnlein O.
Am J Respir Crit Care Med. 2012 Mar 15;185(6):628-36. doi: 10.1164/rccm.201108-1533OC. Epub 2012 Jan 12.

Meta-analysis identifies six new susceptibility loci for atrial fibrillation.

Ellinor PT, Lunetta KL, Albert CM, Glazer NL, Ritchie MD, Smith AV, Arking DE, Müller-Nurasyid M, Krijthe BP, Lubitz SA, Bis JC, Chung MK, Dörr M, Ozaki K, Roberts JD, Smith JG, Pfeufer A, Sinner MF, Lohman K, Ding J, Smith NL, Smith JD, Rienstra M, Rice KM, Van Wagoner DR, Magnani JW, Wakili R, Clauss S, Rotter JI, Steinbeck G, Launer LJ, Davies RW, Borkovich M, Harris TB, Lin H, Völker U, Völzke H, Milan DJ, Hofman A, Boerwinkle E, Chen LY, Soliman EZ, Voight BF, Li G, Chakravarti A, Kubo M, Tedrow UB, Rose LM, Ridker PM, Conen D, Tsunoda T, Furukawa T, Sotoodehnia N, Xu S, Kamatani N, Levy D, Nakamura Y, Parvez B, Mahida S, Furie KL, Rosand J, Muhammad R, Psaty BM, Meitinger T, Perz S, Wichmann HE, Witteman JC, Kao WH, Kathiresan S, Roden DM, Uitterlinden AG, Rivadeneira F, McKnight B, Sjögren M, Newman AB, Liu Y, Gollob MH, Melander O, Tanaka T, Stricker BH, Felix SB, Alonso A, Darbar D, Barnard J, Chasman DI, Heckbert SR, Benjamin EJ, Gudnason V, Kääb S.
Nat Genet. 2012 Apr 29;44(6):670-5. doi: 10.1038/ng.2261.

Triggering of acute myocardial infarction by different means of transportation.
Peters A, von Klot S, Mittleman MA, Meisinger C, Hörmann A, Kuch B, Wichmann HE.
Eur J Prev Cardiol. 2012 Apr 26. [Epub ahead of print]

Repolarization perturbation and hypomagnesaemia after extreme exercise.
Scherr J, Schuster T, Pressler A, Roeh A, Christle J, Wolfarth B, Halle M.
Med Sci Sports Exerc. 2012 Apr 24. [Epub ahead of print]

Monocytes, neutrophils, and platelets cooperate to initiate and propagate venous thrombosis in mice in vivo.
von Brühl ML, Stark K, Steinhart A, Chandraratne S, Konrad I, Lorenz M, Khandoga A, Tirniceriu A, Coletti R, Köllnberger M, Byrne RA, Laitinen I, Walch A, Brill A, Pfeiler S, Manukyan D, Braun S, Lange P, Riegger J, Ware J, Eckart A, Haidari S, Rudelius M, Schulz C, Echtler K, Brinkmann V, Schwaiger M, Preissner KT, Wagner DD, Mackman N, Engelmann B, Massberg S.
J Exp Med. 2012 Apr 9;209(4):819-35.

Molecular diagnosis in mitochondrial complex I deficiency using exome sequencing.
Haack TB, Haberberger B, Frisch EM, Wieland T, Iuso A, Gorza M, Strecker V, Graf E, Mayr JA, Herberg U, Hennermann JB, Klopstock T, Kuhn KA, Ahting U, Sperl W, Wilichowski E, Hoffmann GF, Tesarova M, Hansikova H, Zeman J, Plecko B, Zeviani M, Wittig I, Strom TM, Schuelke M, Freisinger P, Meitinger T, Prokisch H.
J Med Genet. 2012 Apr;49(4):277-83.

A flow cytometric protocol for enumeration of endothelial progenitor cells and monocyte subsets in human blood.
Hristov M, Schmitz S, Nauwelaers F, Weber C.
J Immunol Methods. 2012 Jul 31;381(1-2):9-13. Epub 2012 Apr 13.

Auto-Antigenic Protein-DNA Complexes Stimulate Plasmacytoid Dendritic Cells to Promote Atherosclerosis.
Döring Y, Manthey HD, Drechsler M, Lievens D, Megens RT, Soehnlein O, Busch M, Manca M, Koenen RR, Pelisek J, Daemen MJ, Lutgens E, Zenke M, Binder CJ, Weber C, Zernecke A.
Circulation. 2012 Apr 3;125(13):1673-83.

microRNA expression signatures and parallels between monocyte subsets and atherosclerotic plaque in humans.
Bidzhekov K, Gan L, Denecke B, Rostalsky A, Hristov M, Koeppel TA, Zernecke A, Weber C.
Thromb Haemost. 2012 Apr 3;107(4):619-25.

Long-term effects of an inpatient weight-loss program in obese children and the role of genetic predisposition - Rationale and design of the LOGIC-trial.
Rank M, Siegrist M, Wilks DC, Haller B, Wolfarth B, Langhof H, Halle M.
BMC Pediatr. 2012 Mar 19;12(1):30. [Epub ahead of print]

G protein-mediated stretch reception.
Storch U, Mederos y Schnitzler M, Gudermann T.
Am J Physiol Heart Circ Physiol. 2012 Mar;302(6):H1241-9.

Diabetes and heart failure: a practically oriented critical appraisal.
Halle M, Gitt AK, Hanefeld M, Kellerer M, Marx N, Meier JJ, Schumm-Draeger PM, Bramlage P, Tschoepe D.
Dtsch Med Wochenschr. 2012 Mar;137(9):437-41. German

Retinal vessel diameter, obesity and metabolic risk factors in school children (JuvenTUM 3).
Hanssen H, Siegrist M, Neidig M, Renner A, Birzele P, Siclovan A, Blume K, Lammel C, Haller B, Schmidt-Trucksäss A, Halle M.
Atherosclerosis. 2012 Mar;221(1):242-8.

The HIF1 target gene NOX2 promotes angiogenesis through urotensin-II.
Diebold I, Petry A, Sabrane K, Djordjevic T, Hess J, Görlach A.
J Cell Sci. 2012 Feb 15;125(Pt 4):956-64.

Lack of the mitochondrial protein acylglycerol kinase causes Sengers syndrome.
Mayr JA, Haack TB, Graf E, Zimmermann FA, Wieland T, Haberberger B, Superti-Furga A, Kirschner J, Steinmann B, Baumgartner MR, Moroni I, Lamantea E, Zeviani M, Rodenburg RJ, Smeitink J, Strom TM, Meitinger T, Sperl W, Prokisch H.
Am J Hum Genet. 2012 Feb 10;90(2):314-20.

The use of high-throughput technologies to investigate vascular inflammation and atherosclerosis
Döring Y, Noels H, Weber C.
Arterioscler Thromb Vasc Biol. 2012 Feb;32(2):182-95.

A large candidate gene survey identifies the KCNE1 D85N polymorphism as a possible modulator of drug-induced torsades de pointes.
Kääb S, Crawford DC, Sinner MF, Behr ER, Kannankeril PJ, Wilde AA, Bezzina CR, Schulze-Bahr E, Guicheney P, Bishopric NH, Myerburg RJ, Schott JJ, Pfeufer A, Beckmann BM, Martens E, Zhang T, Stallmeyer B, Zumhagen S, Denjoy I, Bardai A, Van Gelder IC, Jamshidi Y, Dalageorgou C, Marshall V, Jeffery S, Shakir S, Camm AJ, Steinbeck G, Perz S, Lichtner P, Meitinger T, Peters A, Wichmann HE, Ingram C, Bradford Y, Carter S, Norris K, Ritchie MD, George AL Jr, Roden DM.
Circ Cardiovasc Genet. 2012 Feb 1;5(1):91-9.

A phenotypic screen to identify hypertrophy-modulating microRNAs in primary cardiomyocytes.
Jentzsch C, Leierseder S, Loyer X, Flohrschütz I, Sassi Y, Hartmann D, Thum T, Laggerbauer B, Engelhardt S.
J Mol Cell Cardiol. 2012 Jan;52(1):13-20.

Accuracy of dynamic computed tomography adenosine stress myocardial perfusion imaging in estimating myocardial blood flow at various degrees of coronary artery stenosis using a porcine animal model.
Bamberg F, Hinkel R, Schwarz F, Sandner TA, Baloch E, Marcus R, Becker A, Kupatt C, Wintersperger BJ, Johnson TR, Theisen D, Klotz E, Reiser MF, Nikolaou K.
Invest Radiol. 2012 Jan;47(1):71-7.

Extreme exercise enhances chromogranin A levels correlating with stress levels but not with cardiac burden.
Nickel T, Vogeser M, Emslander I, David R, Heilmeier B, Op den Winkel M, Schmidt-Trucksäss A, Wilbert-Lampen U, Hanssen H, Halle M.
Atherosclerosis. 2012 Jan;220(1):219-22.

Mitochondrial thioredoxin reductase is essential for early postischemic myocardial protection.
Horstkotte J, Perisic T, Schneider M, Lange P, Schroeder M, Kiermayer C, Hinkel R, Ziegler T, Mandal PK, David R, Schulz S, Schmitt S, Widder J, Sinowatz F, Becker BF, Bauersachs J, Naebauer M, Franz WM, Jeremias I, Brielmeier M, Zischka H, Conrad M, Kupatt C.
Circulation. 2011 Dec 20;124(25):2892-902.

Chemokines: established and novel targets in atherosclerosis.
Koenen RR, Weber C.
EMBO Mol Med. 2011 Dec;3(12):713-25.

Acute and chronic effects of marathon running on the retinal microcirculation.
Pressler A, Hanssen H, Dimitrova M, Krumm M, Halle M, Scherr J.
Atherosclerosis. 2011 Dec;219(2):864-8.

NOX4 mediates activation of FoxO3a and matrix metalloproteinase-2 expression by urotensin-II.
Diebold I, Petry A, Burger M, Hess J, Görlach A.
Mol Biol Cell. 2011 Nov;22(22):4424-34.

Double-edged role of the CXCL12/CXCR4 axis in experimental myocardial infarction.
Liehn EA, Tuchscheerer N, Kanzler I, Drechsler M, Fraemohs L, Schuh A, Koenen RR, Zander S, Soehnlein O, Hristov M, Grigorescu G, Urs AO, Leabu M, Bucur I, Merx MW, Zernecke A, Ehling J, Gremse F, Lammers T, Kiessling F, Bernhagen J, Schober A, Weber C.
J Am Coll Cardiol. 2011 Nov 29;58(23):2415-23.

Differential role of monocyte subsets in atherosclerosis.
Hristov M, Weber C.
Thromb Haemost. 2011 Nov;106(5):757-62.

Atherosclerosis: current pathogenesis and therapeutic options.
Weber C, Noels H.
Nat Med. 2011 Nov 7;17(11):1410-22.

CD40L deficiency ameliorates adipose tissue inflammation and metabolic manifestations of obesity in mice.
Poggi M, Engel D, Christ A, Beckers L, Wijnands E, Boon L, Driessen A, Cleutjens J, Weber C, Gerdes N, Lutgens E.
Arterioscler Thromb Vasc Biol. 2011 Oct;31(10):2251-60.

ApoE controls the interface linking lipids and inflammation in atherosclerosis.
Weber C, Soehnlein O.
J Clin Invest. 2011 Oct;121(10):3825-7.

Microparticles from apoptotic platelets promote resident macrophage differentiation.
Vasina EM, Cauwenberghs S, Feijge MA, Heemskerk JW, Weber C, Koenen RR.
Cell Death Dis. 2011 Sep 29;2:e211.

Critical role for stromal interaction molecule 1 in cardiac hypertrophy.
Hulot JS, Fauconnier J, Ramanujam D, Chaanine A, Aubart F, Sassi Y, Merkle S, Cazorla O, Ouillé A, Dupuis M, Hadri L, Jeong D, Mühlstedt S, Schmitt J, Braun A, Bénard L, Saliba Y, Laggerbauer B, Nieswandt B, Lacampagne A, Hajjar RJ, Lompré AM, Engelhardt S.
Circulation. 2011 Aug 16;124(7):796-805.

A polymorphism-specific "memory" mechanism in the β(2)-adrenergic receptor.
Ahles A, Rochais F, Frambach T, Bünemann M, Engelhardt S.
Sci Signal. 2011 Aug 9;4(185):ra53.

 

 

 

 

http://www.ncbi.nlm.nih.gov/pubmed/23797373